SCHEMBL31667484

SCHEMBL31667484

COc1ccc(-c2noc(N3CCC(C(=O)NCC4CCN(Cc5ccc(C)cn5)C4)CC3)n2)cc1

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.56
▸ KMT2A Q03164 4/20 0.56
▸ MAPT P10636 3/20 0.54
▸ LMNA P02545 2/20 0.53
▸ SMN1; SMN2 Q16637 2/20 0.52
▸ POLB P06746 1/20 0.48
▸ TP53 P04637 2/20 0.48
▸ KDM4E B2RXH2 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.48
▸ HTT P42858 1/20 0.48
▸ HSD17B10 Q99714 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL31546359 0.97 MEN1 (0.54) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL31546440 0.92 MEN1 (0.55) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL30584854 0.91 MAPT (0.47) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL25437981 0.89 LMNA (0.59) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL30584763 0.89 MAPT (0.45) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL30584894 0.89 MEN1 (0.55) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL31667383 0.89 MEN1 (0.57) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL31667355 0.88 LMNA (0.58) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL30584734 0.87 MAPT (0.58) MEN1KMT2AMAPTLMNASMN1; SMN2
SCHEMBL31546403 0.87 MEN1 (0.56) MEN1KMT2AMAPTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP claimed
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
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