SCHEMBL31546440

SCHEMBL31546440

COc1ccc(-c2noc(N3CCC(C(=O)NCC4CCN(Cc5ccc(F)cn5)C4)CC3)n2)cc1

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 5/20 0.55
▸ KMT2A Q03164 5/20 0.55
▸ POLB P06746 1/20 0.55
▸ LMNA P02545 2/20 0.52
▸ MAPT P10636 2/20 0.51
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ RAB9A P51151 1/20 0.50
▸ TP53 P04637 1/20 0.49
▸ THRB P10828 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31667484 0.92 MEN1 (0.56) MEN1KMT2APOLBLMNAMAPT
SCHEMBL31546367 0.90 POLB (0.60) MEN1KMT2APOLBLMNAMAPT
Formic Acid SCHEMBL31546359 0.89 MEN1 (0.54) MEN1KMT2APOLBLMNAMAPT
SCHEMBL31667383 0.88 MEN1 (0.57) MEN1KMT2APOLBLMNAMAPT
SCHEMBL31546319 0.86 MEN1 (0.55) MEN1KMT2APOLBLMNAMAPT
SCHEMBL30584858 0.86 MEN1 (0.56) MEN1KMT2APOLBLMNAMAPT
SCHEMBL31667355 0.86 LMNA (0.58) MEN1KMT2APOLBLMNAMAPT
Formic Acid SCHEMBL25434989 0.86 MEN1 (0.54) MEN1KMT2APOLBLMNAMAPT
SCHEMBL25435818 0.86 MEN1 (0.60) MEN1KMT2APOLBLMNAMAPT
SCHEMBL31546445 0.85 POLB (0.57) MEN1KMT2APOLBLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP claimed
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 MEN1 1569/4885KMT2A 1404/4885POLB 1664/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 MEN1 1569/4885KMT2A 1404/4885POLB 1664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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