SCHEMBL31667452

SCHEMBL31667452

Cc1conc1CC1c2ccccc2C(=O)N1Cc1ccc2[nH]c(=O)oc2c1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ IL4I1 Q96RQ9 1/20 0.37
▸ HPGD P15428 3/20 0.36
▸ NOS1 P29475 1/20 0.34
▸ MAPT P10636 4/20 0.34
▸ MEN1 O00255 3/20 0.34
▸ KMT2A Q03164 3/20 0.34
▸ LMNA P02545 2/20 0.34
▸ GRIN1 Q05586 1/20 0.34
▸ HTT P42858 1/20 0.33
▸ MAPK1 P28482 3/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ OGT O15294 1/20 0.32
▸ TSHR P16473 2/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ PDE10A Q9Y233 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31667623 0.86 IL4I1 (0.39) IL4I1HPGDNOS1MAPTMEN1
SCHEMBL31667612 0.86 IL4I1 (0.39) IL4I1HPGDNOS1MAPTMEN1
SCHEMBL31667029 0.86 IL4I1 (0.37) IL4I1HPGDNOS1MAPTMEN1
SCHEMBL31667349 0.86 IL4I1 (0.39) IL4I1HPGDNOS1MAPTMEN1
SCHEMBL31667297 0.85 IL4I1 (0.38) IL4I1HPGDNOS1MAPTMEN1
SCHEMBL31666968 0.84 IL4I1 (0.44) IL4I1HPGDNOS1MAPTMEN1
SCHEMBL31667330 0.83 IL4I1 (0.37) IL4I1HPGDNOS1MAPTMEN1
SCHEMBL31667717 0.83 MEN1 (0.45) IL4I1HPGDMAPTMEN1KMT2A
SCHEMBL31666930 0.83 MEN1 (0.45) IL4I1HPGDMAPTMEN1KMT2A
SCHEMBL31667679 0.83 MEN1 (0.45) IL4I1HPGDMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078130-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF SIRONAX LTD (KY) 2026-03-19 — — US disclosed
EP-4590674-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd (KY) 2025-07-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078130-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF NAMPT, NNMT, SARM1 IL4I1 2872/4885HPGD 520/4885NOS1 2579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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