Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14315830 | 1.00 | TSHR (0.48) | TSHRNAAAEPHX1ALDH1A1HTR2C | |
| SCHEMBL14315869 | 1.00 | TSHR (0.48) | TSHRNAAAEPHX1ALDH1A1HTR2C | |
| SCHEMBL7781605 | 0.98 | NAAA (0.52) | TSHRNAAAEPHX1ALDH1A1HTR2C | |
| SCHEMBL2214933 | 0.98 | NAAA (0.52) | TSHRNAAAEPHX1ALDH1A1HTR2C | |
| SCHEMBL7782942 | 0.98 | NAAA (0.52) | TSHRNAAAEPHX1ALDH1A1HTR2C | |
| SCHEMBL18672810 | 0.98 | NAAA (0.52) | TSHRNAAAEPHX1ALDH1A1HTR2C | |
| SCHEMBL2214927 | 0.98 | NAAA (0.52) | TSHRNAAAEPHX1ALDH1A1HTR2C | |
| SCHEMBL7782139 | 0.98 | NAAA (0.52) | TSHRNAAAEPHX1ALDH1A1HTR2C | |
| SCHEMBL7782136 | 0.98 | NAAA (0.52) | TSHRNAAAEPHX1ALDH1A1HTR2C | |
| SCHEMBL31584710 | 0.98 | NAAA (0.52) | TSHRNAAAEPHX1ALDH1A1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520195-B | Novel nucleoside phosphonate prodrugs | 勒芬天主教大学 | 2023-01-17 | — | — | CN | claimed |
| CN-115197148-B | 5-benzyl imidazole compound and preparation method and application thereof | 四川大学华西医院 | 2023-12-12 | — | — | CN | disclosed |
| CN-110520195-B | Novel nucleoside phosphonate prodrugs | 勒芬天主教大学 | 2023-01-17 | — | — | CN | disclosed |
| EP-3600556-A1 | NOVEL PRODRUGS OF NUCLEOSIDE PHOSPHONATES | Katholieke Universiteit Leuven (BE) | 2020-02-05 | — | — | EP | disclosed |
| CN-110520195-A | Novel nucleoside phosphonate prodrugs | UNIV LEUVEN KATH | 2019-11-29 | — | — | CN | disclosed |
| WO-2018172416-A1 | NOVEL PRODRUGS OF NUCLEOSIDE PHOSPHONATES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2018-09-27 | — | — | WO | disclosed |
| EP-2860176-B1 | HETEROCYCLIC GROUP CONTAINED AMINO-METHANOL DERIVATIVE, AND SALT, SYNTHETIC METHOD AND USE THEREOF | BEIJING FORELAND BIOPHARMA CO LTD (CN) | 2017-09-27 | — | — | EP | disclosed |
| CN-107148216-A | Pesticidal formulations | 石原产业株式会社 | 2017-09-08 | — | — | CN | disclosed |
| US-9315492-B2 | Heterocyclic group contained amino-methanol derivative, and salt, synthetic method and use thereof | BEIJING FORELAND BIOPHARMA CO., LTD. (CN) | 2016-04-19 | — | — | US | disclosed |
| EP-2860176-A1 | HETEROCYCLIC GROUP CONTAINED AMINO-METHANOL DERIVATIVE, AND SALT, SYNTHETIC METHOD AND USE THEREOF | Beijing Foreland Biopharma Co., Ltd. (CN) | 2015-04-15 | — | — | EP | disclosed |
| US-20150094337-A1 | HETEROCYCLIC GROUP CONTAINED AMINO-METHANOL DERIVATIVE, AND SALT, SYNTHETIC METHOD AND USE THEREOF | BEIJING FORELAND BIOPHARMA CO., LTD. (CN) | 2015-04-02 | — | — | US | disclosed |
| WO-2010088573-A1 | CYCLOSPORIN ANALOGUES FOR PREVENTING OR TREATING HEPATITIS C INFECTION | ENANTA PHARMACEUTICALS, INC. (US) | 2010-08-05 | — | — | WO | disclosed |
| US-7718598-B1 | Auxiliary for amide bond formation | THE UNIVERSITY OF QUEENSLAND (AU) | 2010-05-18 | — | — | US | disclosed |
| EP-1115739-B1 | AUXILIARY FOR AMIDE BOND FORMATION | UNIV QUEENSLAND (AU) | 2009-04-29 | — | — | EP | disclosed |
| EP-1115739-A4 | AUXILIARY FOR AMIDE BOND FORMATION | UNIV QUEENSLAND (AU) | 2004-10-27 | — | — | EP | disclosed |
| EP-1115739-A1 | AUXILIARY FOR AMIDE BOND FORMATION | THE UNIVERSITY OF QUEENSLAND (AU) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018789-A1 | AUXILIARY FOR AMIDE BOND FORMATION | THE UNIVERSITY OF QUEENSLAND (AU) | 2000-04-06 | — | — | WO | disclosed |
| US-3954845-A | Synthetic detergents of the ampholytic betaine type, process for preparing the same and compositions | MODOKEMI AKTIEBOLAG (SW) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150094337-A1 | HETEROCYCLIC GROUP CONTAINED AMINO-METHANOL DERIVATIVE, AND SALT, SYNTHETIC METHOD AND USE THEREOF | SSB, HLA-DRB1, MYD88 | TSHR 2212/4885NAAA 626/4885EPHX1 4311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.