Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.40 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.40 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.40 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | CPS1 | P31327 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17608679 | 1.00 | RAB9A (0.43) | RAB9AKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL17800777 | 0.88 | LMNA (0.47) | KMT2AMEN1LMNAMAPK1GFER | |
| SCHEMBL31672347 | 0.88 | LMNA (0.47) | KMT2AMEN1LMNAMAPK1GFER | |
| SCHEMBL31672351 | 0.86 | CPS1 (0.43) | KMT2AMEN1LMNAMAPK1GFER | |
| SCHEMBL17800778 | 0.86 | CPS1 (0.43) | KMT2AMEN1LMNAMAPK1GFER | |
| SCHEMBL17800783 | 0.85 | BTK (0.40) | RAB9AKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL31672378 | 0.85 | BTK (0.40) | RAB9AKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL17800784 | 0.85 | BTK (0.40) | RAB9AKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL31672384 | 0.84 | RAB9A (0.44) | RAB9AKMT2ALMNATSHRALDH1A1 | |
| SCHEMBL17608599 | 0.84 | RAB9A (0.44) | RAB9AKMT2ALMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE50527-E1 | Covalent inhibitors of KRAS G12C | ARAXES PHARMA LLC (US) | 2025-08-12 | — | — | US | disclosed |