Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 18/20 | 0.77 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16100135 | 1.00 | KRAS (0.77) | KRASEGLN1 | |
| SCHEMBL31672331 | 0.89 | KRAS (0.83) | KRAS | |
| SCHEMBL16100289 | 0.89 | KRAS (0.83) | KRAS | |
| SCHEMBL16122668 | 0.89 | KRAS (0.60) | KRAS | |
| SCHEMBL31672334 | 0.88 | KRAS (1.00) | KRASEGLN1 | |
| SCHEMBL16103039 | 0.88 | KRAS (1.00) | KRASEGLN1 | |
| SCHEMBL20260100 | 0.85 | KRAS (0.55) | KRAS | |
| SCHEMBL16102399 | 0.85 | KRAS (0.83) | KRAS | |
| SCHEMBL16117843 | 0.84 | KRAS (0.85) | KRASEGLN1 | |
| SCHEMBL31672380 | 0.84 | KRAS (0.85) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE50527-E1 | Covalent inhibitors of KRAS G12C | ARAXES PHARMA LLC (US) | 2025-08-12 | — | — | US | disclosed |