Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 14/20 | 0.83 |
| ▸ | CDK14 | O94921 | 1/20 | 0.38 |
| ▸ | CCNY | Q8ND76 | 1/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16117832 | 1.00 | KRAS (0.83) | KRASCDK14CCNYSHMT2EGLN1 | |
| SCHEMBL16117744 | 0.96 | KRAS (0.86) | KRASCDK14CCNYSHMT2EGLN1 | |
| SCHEMBL16117714 | 0.93 | KRAS (0.92) | KRASSHMT2 | |
| SCHEMBL16103039 | 0.91 | KRAS (1.00) | KRASEGLN1 | |
| SCHEMBL31672334 | 0.91 | KRAS (1.00) | KRASEGLN1 | |
| SCHEMBL16122667 | 0.90 | KRAS (0.83) | KRASCDK14CCNYSHMT2ERBB2 | |
| SCHEMBL30642292 | 0.88 | KRAS (0.76) | KRASCDK14CCNYEGLN1SCD | |
| SCHEMBL16117835 | 0.88 | KRAS (0.74) | KRASSHMT2EGLN1ERBB2 | |
| SCHEMBL31672361 | 0.88 | KRAS (0.74) | KRASSHMT2EGLN1ERBB2 | |
| SCHEMBL16117838 | 0.88 | KRAS (0.76) | KRASCDK14CCNYEGLN1SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE50527-E1 | Covalent inhibitors of KRAS G12C | ARAXES PHARMA LLC (US) | 2025-08-12 | — | — | US | disclosed |