SCHEMBL316729

SCHEMBL316729

CC(C)N(OC(=O)C(Cl)Cl)C(C)C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27684303 0.95
SCHEMBL5671706 0.77 TP53 (0.36)
SCHEMBL216434 0.75 TP53 (0.35)
SCHEMBL2800618 0.75 TP53 (0.35)
SCHEMBL8871105 0.73 TSHR (0.30)
SCHEMBL27465287 0.73 TSHR (0.30)
SCHEMBL3362691 0.71 HTT (0.30)
SCHEMBL6377049 0.71 HTT (0.30)
SCHEMBL2254132 0.70 TSHR (0.41)
SCHEMBL10932775 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119708799-B Cured product of organic phosphine modified unsaturated polyester and polyhalide and preparation method thereof 浙江工业大学 2025-05-30 CN claimed
CN-119708799-A Cured product of organic phosphine modified unsaturated polyester and polyhalide and preparation method thereof 浙江工业大学 2025-03-28 CN claimed
WO-2023183932-A2 MONOBODIES BINDING TO INTERCELLULAR ADHESION MOLECULE 2 (ICAM-2) NEW YORK UNIVERSITY (US) 2023-09-28 WO claimed
CN-116687912-A Use of gomisin N and derivatives thereof in the treatment of liver injury related diseases 上海交通大学医学院附属第九人民医院 2023-09-05 CN claimed
CN-115887390-A Diisopropylamine dichloroacetate sodium gluconate freeze-dried composition for injection and application 山东北大高科华泰制药有限公司 2023-04-04 CN claimed
CN-115737633-A Traditional Chinese medicine active monomer with liver protection effect and application thereof 上海交通大学医学院附属第九人民医院 2023-03-07 CN claimed
CN-114892357-A Antibacterial anti-aging textile material, preparation method and device 江门职业技术学院 2022-08-12 CN claimed
EP-3485908-B1 THERAPEUTIC COMBINATION AND USE OF DLL4 ANTAGONIST ANTIBODIES AND ANTI-HYPERTENSIVE AGENTS MEREO BIOPHARMA 5 INC (US) 2021-08-18 EP claimed
CN-109806263-A A kind of pharmaceutical composition and its preparation method and application 中国药科大学 2019-05-28 CN claimed
CN-109419692-A A kind of ecchymose removing dampness elimination gas shin moisturizer 汕头市精湛财务咨询有限公司 2019-03-05 CN claimed
CN-1443575-A Medicine for curing metabolic syndrome LIAONING YILIAN NEW MEDICINE I (CN) 2003-09-24 CN claimed
US-20030162824-A1 Methods of treating or preventing a cardiovascular condition using a cyclooxygenase-1 inhibitor PHARMACIA CORPORATION 2003-08-28 US claimed
CN-1433766-A Medicine for treating metabolism syndrome LIAONING YILIAN NOVEL MEDICINE (CN) 2003-08-06 CN claimed
WO-2002087556-A9 PROBUCOL MONOESTERS AND THEIR USE TO INCREASE PLASMA HDL CHOLESTEROL LEVELS AND IMPROVE HDL FUNCTIONALITY ATHEROGENICS INC (US) 2003-03-20 WO claimed
WO-2002087556-A2 PROBUCOL MONOESTERS AND THEIR USE TO INCREASE PLASMA HDL CHOLESTEROL LEVELS AND IMPROVE HDL FUNCTIONALITY ATHEROGENICS, INC. (US) 2002-11-07 WO claimed
WO-2002072039-A2 TOPICAL PREPARATIONS AND FOOD PREPARATIONS COMPRISING A PYRIDOXINE-ALPHA-D-GLUCOSE PENTAPHARM LTD (CH) 2002-09-19 WO claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
US-5811547-A Method for inducing crystalline state transition in medicinal substance NIPPON SHINYAJU CO., LTD. (JP) 1998-09-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162824-A1 Methods of treating or preventing a cardiovascular condition using a cyclooxygenase-1 inhibitor PTGS1, PTGIS, TNNT2 LMNA 1336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.