Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | SCN1A | P35498 | 1/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.65 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.65 |
| ▸ | GHSR | Q92847 | 1/20 | 0.65 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.65 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | DHODH | Q02127 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6250517 | 1.00 | KDM4E (0.65) | KDM4EALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL9198147 | 0.96 | HTR3E (0.61) | KDM4EALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL29176330 | 0.95 | HTR3E (0.61) | KDM4EALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL9198080 | 0.95 | HTR3E (0.61) | KDM4EALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL7939470 | 0.93 | PDE10A (0.65) | KDM4EALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL28378761 | 0.89 | KDM4E (0.62) | KDM4EALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL9200082 | 0.88 | HTR3E (0.62) | KDM4EALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL13490841 | 0.88 | KDM4E (0.55) | KDM4EALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL9203821 | 0.87 | KDM4E (0.64) | KDM4EALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL29176351 | 0.83 | HTR3E (0.64) | KDM4EALDH1A1LMNASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250259704-A1 | SYSTEMS AND METHODS FOR CELL-FREE ITERATIVE SITE SATURATION MUTAGENESIS AND ITS APPLICATION FOR THE DIRECTED EVOLUTION OF ENZYMES CATALYZING UNNATURAL REACTIONS | U.S. DEPARTMENT OF ENERGY | 2025-08-14 | — | — | US | disclosed |