SCHEMBL316736

SCHEMBL316736

C[C@H]1CCCCCCCCCCCCC(=O)C1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.54
CA1 P00915 2/20 0.50
CA2 P00918 1/20 0.50
CA4 P22748 1/20 0.50
TRIM24 O15164 2/20 0.46
TRIM33 Q9UPN9 2/20 0.46
ALDH1A1 P00352 2/20 0.46
THRB P10828 1/20 0.35
TLR4 O00206 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
CRBN Q96SW2 1/20 0.32
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
LMNA P02545 1/20 0.30
HSP90AA1 P07900 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11812189 1.00 KMT2A (0.54) KMT2ACA1CA2CA4TRIM24
SCHEMBL2196645 1.00 KMT2A (0.54) KMT2ACA1CA2CA4TRIM24
SCHEMBL14118250 1.00 KMT2A (0.54) KMT2ACA1CA2CA4TRIM24
SCHEMBL14118041 1.00 KMT2A (0.54) KMT2ACA1CA2CA4TRIM24
SCHEMBL230871 1.00 KMT2A (0.54) KMT2ACA1CA2CA4TRIM24
SCHEMBL24304032 1.00 KMT2A (0.54) KMT2ACA1CA2CA4TRIM24
SCHEMBL1870048 1.00 KMT2A (0.54) KMT2ACA1CA2CA4TRIM24
SCHEMBL14344239 1.00 KMT2A (0.54) KMT2ACA1CA2CA4TRIM24
SCHEMBL7739757 1.00 KMT2A (0.54) KMT2ACA1CA2CA4TRIM24
SCHEMBL5421215 1.00 KMT2A (0.54) KMT2ACA1CA2CA4TRIM24

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1264594-B1 Melanin production inhibitors and skincare products containing such inhibitors TAKASAGO PERFUMERY CO LTD (JP) 2006-11-29 EP claimed
US-6759557-B2 MACROCYCLIC HYDROCARBON RINGS WITH HYDROXYL AND/OR KETONE FUNCTIONALITIES, SUCH AS CYCLOTETRADECANONE OR 2-HYDROXYCYCLOHEXADECANONE, OPTIONALLY WITH SKIN WHITENING AGENTS AND/OR UV ABSORBERS TAKASAGO INTERNATIONAL CORPORATION (JP) 2004-07-06 US claimed
US-20030049213-A1 Melanin production inhibitors and skincare products containing such inhibitors TAKASAGO INTERNATIONAL CORPORATION (JP) 2003-03-13 US claimed
EP-1264594-A2 Melanin production inhibitors and skincare products containing such inhibitors Takasago International Corporation (JP) 2002-12-11 EP claimed
CN-117890409-A Method for identifying musk and musk ketone in musk preparation 漳州片仔癀药业股份有限公司 2024-04-16 CN disclosed
CN-109640700-B Perfume composition, food and drink, and method for producing food and drink 高砂香料工业株式会社 2023-04-11 CN disclosed
CN-105916970-B Powdery musk odorant macrocycles 弗门尼舍有限公司 2019-12-10 CN disclosed
US-10087395-B2 Use of hexadeca-8,15-dienal as aroma chemical BASF SE (DE) 2018-10-02 US disclosed
EP-3206756-B1 USE OF HEXADECA-8,15-DIENAL AS AN AROMA CHEMICAL BASF SE (DE) 2018-09-19 EP disclosed
US-20170362532-A1 USE OF HEXADECA-8,15-DIENAL AS AROMA CHEMICAL BASF SE (DE) 2017-12-21 US disclosed
EP-3206756-A1 USE OF HEXADECA-8,15-DIENAL AS AROMA CHEMICAL BASF SE (DE) 2017-08-23 EP disclosed
WO-2016059042-A1 USE OF HEXADECA-8,15-DIENAL AS AROMA CHEMICAL BASF SE (DE) 2016-04-21 WO disclosed
US-20090143485-A1 OPTICALLY ACTIVE MUSCONE COMPOSITION AND FRAGRANCES OR COSMETICS CONTAINING THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-06-04 US disclosed
EP-1820842-A1 OPTICALLY ACTIVE MUSCONE COMPOSITION AND PERFUME PRODUCT CONTAINING THE SAME Takasago International Corporation (JP) 2007-08-22 EP disclosed
EP-1264594-B1 Melanin production inhibitors and skincare products containing such inhibitors TAKASAGO PERFUMERY CO LTD (JP) 2006-11-29 EP disclosed
CN-1836670-A Microsphere injection for treating ophthalmopathy DUAN YADONG (CN) 2006-09-27 CN disclosed
US-20050271608-A1 Skin whitening compositions based on hydroxyaryl alkyl ketones and their isosteric derivatives GUPTA SHYAM K 2005-12-08 US disclosed
US-6759557-B2 MACROCYCLIC HYDROCARBON RINGS WITH HYDROXYL AND/OR KETONE FUNCTIONALITIES, SUCH AS CYCLOTETRADECANONE OR 2-HYDROXYCYCLOHEXADECANONE, OPTIONALLY WITH SKIN WHITENING AGENTS AND/OR UV ABSORBERS TAKASAGO INTERNATIONAL CORPORATION (JP) 2004-07-06 US disclosed
US-20030049213-A1 Melanin production inhibitors and skincare products containing such inhibitors TAKASAGO INTERNATIONAL CORPORATION (JP) 2003-03-13 US disclosed
EP-1264594-A2 Melanin production inhibitors and skincare products containing such inhibitors Takasago International Corporation (JP) 2002-12-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170362532-A1 USE OF HEXADECA-8,15-DIENAL AS AROMA CHEMICAL SCD5, CYP8B1, ELOVL5 KMT2A 1127/4885CA1 2010/4885CA2 4364/4885
US-10087395-B2 Use of hexadeca-8,15-dienal as aroma chemical SCD5, CYP8B1, ELOVL5 KMT2A 1127/4885CA1 2010/4885CA2 4364/4885
US-20030049213-A1 Melanin production inhibitors and skincare products containing such inhibitors TYR, AOC3, DOHH KMT2A 1713/4885CA1 4605/4885CA2 3711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.