Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.45 |
| ▸ | VNN1 | O95497 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17247657 | 0.81 | APLNR (0.52) | NPC1MAPTRAB9ALMNAMEN1 | |
| SCHEMBL14734428 | 0.80 | KDM4E (0.54) | PDE5AMAPTHTTMEN1KMT2A | |
| SCHEMBL30050379 | 0.80 | MAPT (0.51) | PDE5ANPC1MAPTRAB9ALMNA | |
| SCHEMBL14734451 | 0.80 | MAPT (0.51) | PDE5ANPC1MAPTRAB9ALMNA | |
| SCHEMBL23015389 | 0.78 | PDE5A (0.50) | PDE5ANPC1MAPTRAB9ALMNA | |
| SCHEMBL29692343 | 0.78 | PDE5A (0.50) | PDE5ANPC1MAPTRAB9ALMNA | |
| SCHEMBL31184598 | 0.78 | PRUNE1 (0.46) | PDE5ANPC1MAPTRAB9ALMNA | |
| SCHEMBL31184725 | 0.77 | NPC1 (0.45) | PDE5ANPC1MAPTRAB9ALMNA | |
| SCHEMBL31184765 | 0.76 | MAPT (0.49) | NPC1MAPTRAB9ALMNAL3MBTL1 | |
| SCHEMBL3755765 | 0.75 | PDE5A (0.65) | PDE5AHTTMEN1KMT2AMAP2K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120483924-A | Synthesis method of 3-amino-4-methyl-6-chloropyridazine | 上海毕得医药科技股份有限公司 | 2025-08-15 | — | — | CN | disclosed |