Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 12/20 | 0.50 |
| ▸ | KIT | P10721 | 5/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3167701 | 0.87 | KIT (0.43) | CSF1RKITNTRK1LCKAXL | |
| Trifluoroacetic Acid SCHEMBL3167687 | 0.83 | KIT (0.41) | CSF1RKITNTRK1LCKAXL | |
| SCHEMBL3172739 | 0.82 | CSF1R (0.49) | CSF1RKITNTRK1LCKAXL | |
| SCHEMBL2176780 | 0.80 | CSF1R (0.62) | CSF1RKIT | |
| SCHEMBL13523878 | 0.80 | CSF1R (0.60) | CSF1RKITNTRK1LCKAXL | |
| SCHEMBL310145 | 0.76 | INSR (0.44) | CSF1RKITNTRK1LCKAXL | |
| SCHEMBL2175761 | 0.75 | CSF1R (0.68) | CSF1RKIT | |
| SCHEMBL5651875 | 0.75 | CSF1R (0.67) | CSF1RKIT | |
| SCHEMBL3086038 | 0.74 | CSF1R (0.63) | CSF1RKITNTRK1LCKAXL | |
| SCHEMBL2913376 | 0.73 | CSF1R (0.64) | CSF1RKITNTRK1LCKAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645755-B2 | Inhibitors of c-fms kinase | JANSSEN PHARMACEUTICAL N.V. (BE) | 2010-01-12 | — | — | US | claimed |
| US-20060189623-A1 | Inhibitors of c-fms kinase | ILLIG CARL R | 2006-08-24 | — | — | US | claimed |
| US-7645755-B2 | Inhibitors of c-fms kinase | JANSSEN PHARMACEUTICAL N.V. (BE) | 2010-01-12 | — | — | US | disclosed |
| US-20060189623-A1 | Inhibitors of c-fms kinase | ILLIG CARL R | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189623-A1 | Inhibitors of c-fms kinase | MUSK, TYK2, FES | CSF1R 34/4885KIT 125/4885NTRK1 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.