Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 18/20 | 0.66 |
| ▸ | CRBN | Q96SW2 | 18/20 | 0.66 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26925285 | 0.87 | DDB1 (0.65) | DDB1CRBNPOLB | |
| SCHEMBL30706220 | 0.87 | DDB1 (0.65) | DDB1CRBNPOLB | |
| SCHEMBL24548260 | 0.80 | CRBN (1.00) | DDB1CRBNPOLB | |
| SCHEMBL30993782 | 0.80 | CRBN (0.68) | DDB1CRBNPOLB | |
| SCHEMBL31678103 | 0.79 | DDB1 (0.53) | DDB1CRBN | |
| Hydrochloric Acid SCHEMBL30430104 | 0.78 | CRBN (0.97) | DDB1CRBNPOLB | |
| Hydrochloric Acid SCHEMBL25204069 | 0.78 | CRBN (0.97) | DDB1CRBNPOLB | |
| SCHEMBL8708396 | 0.77 | DDB1 (0.68) | DDB1CRBNPOLB | |
| SCHEMBL24848417 | 0.77 | CRBN (0.68) | DDB1CRBNPOLB | |
| SCHEMBL21934060 | 0.77 | CRBN (0.68) | DDB1CRBNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270191-A1 | QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. | 2025-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270191-A1 | QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | BCL6, BCL6B, BCOR | DDB1 141/4885CRBN 756/4885PARP1 979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.