SCHEMBL31679015

SCHEMBL31679015

NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)[C@@H](N)Cc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 1/20 0.55
▸ DPP8 Q6V1X1 2/20 0.52
▸ DPP7 Q9UHL4 2/20 0.52
▸ SIRT2 Q8IXJ6 1/20 0.52
▸ FOLH1 Q04609 2/20 0.52
▸ ANPEP P15144 1/20 0.51
▸ CPB1 P15086 1/20 0.49
▸ CPB2 Q96IY4 1/20 0.49
▸ CA1 P00915 1/20 0.47
▸ CA2 P00918 1/20 0.47
▸ DPP4 P27487 1/20 0.47
▸ DPP9 Q86TI2 1/20 0.47
▸ MMP2 P08253 1/20 0.47
▸ MMP9 P14780 1/20 0.47
▸ PTGER4 P35408 2/20 0.46
▸ SLC1A3 P43003 1/20 0.46
▸ SLC1A1 P43005 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17073781 0.90 CTSL (0.63) CTSLDPP8DPP7SIRT2FOLH1
SCHEMBL31679037 0.89 CTSL (0.53) CTSLPTGER4
SCHEMBL31679026 0.89 CTSL (0.52) CTSLDPP8DPP7SIRT2FOLH1
SCHEMBL31679029 0.85 MAPT (0.54) CTSLSIRT2
SCHEMBL16869913 0.84 ANPEP (0.61) CTSLDPP8DPP7SIRT2FOLH1
SCHEMBL20794742 0.83 ANPEP (0.60) CTSLDPP8DPP7SIRT2FOLH1
SCHEMBL9498688 0.83 FOLH1 (0.67) DPP8DPP7SIRT2FOLH1ANPEP
SCHEMBL18659611 0.82 CTSL (0.66) CTSLSIRT2FOLH1ANPEPCPB1
Hydrochloric Acid SCHEMBL30340169 0.82 SIRT2 (0.60) CTSLDPP8DPP7SIRT2FOLH1
SCHEMBL21627096 0.82 CTSL (0.54) CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12404300-B2 Mitochondria-targeting peptides STEALTH BIOTHERAPEUTICS INC. (US) 2025-09-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12404300-B2 Mitochondria-targeting peptides SSBP1, HSPE1, IMMT CTSL 1491/4885DPP8 1568/4885DPP7 1306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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