Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.48 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 4/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | CALCR | P30988 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31679475 | 0.95 | MAPK8 (0.56) | MAPK8MAPK9MAPK10OPRD1REN | |
| SCHEMBL31679418 | 0.95 | OPRD1 (0.54) | MAPK8MAPK9MAPK10OPRD1AGTR1 | |
| SCHEMBL31679461 | 0.95 | MAPK8 (0.50) | MAPK8MAPK9MAPK10OPRD1IL23R | |
| SCHEMBL31679423 | 0.95 | AGTR2 (0.51) | MAPK8MAPK9MAPK10OPRD1IL23R | |
| SCHEMBL31679442 | 0.94 | MAPK8 (0.51) | MAPK8MAPK9MAPK10OPRD1AGTR1 | |
| SCHEMBL31679451 | 0.93 | AGTR2 (0.52) | MAPK8MAPK9MAPK10OPRD1AGTR1 | |
| SCHEMBL31679462 | 0.93 | AGTR2 (0.52) | MAPK8MAPK9MAPK10OPRD1IL23R | |
| SCHEMBL31679406 | 0.92 | MAPK8 (0.51) | MAPK8MAPK9MAPK10OPRD1IL23R | |
| SCHEMBL31679349 | 0.92 | OPRD1 (0.51) | OPRD1IL23ROPRM1 | |
| SCHEMBL31679381 | 0.92 | AGTR2 (0.50) | MAPK8MAPK9MAPK10OPRD1AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4610269-A1 | UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR (UPAR) LIGANDS FOR DIAGNOSTIC OR THERAPEUTIC USE | 3B Pharmaceuticals GmbH (DE) | 2025-09-03 | — | — | EP | disclosed |