Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.49 |
| ▸ | NTSR2 | O95665 | 3/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.49 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.48 |
| ▸ | NMUR2 | Q9GZQ4 | 3/20 | 0.47 |
| ▸ | NMUR1 | Q9HB89 | 3/20 | 0.47 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.47 |
| ▸ | NPY4R | P50391 | 3/20 | 0.47 |
| ▸ | NPY1R | P25929 | 2/20 | 0.47 |
| ▸ | NPY2R | P49146 | 2/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31679415 | 0.97 | MAPK8 (0.47) | MAPK8MAPK9MAPK10KEAP1NTSR2 | |
| SCHEMBL31679441 | 0.94 | NTSR1 (0.51) | MAPK8MAPK9MAPK10KEAP1NTSR2 | |
| SCHEMBL31679452 | 0.93 | F2 (0.49) | MAPK8MAPK9MAPK10KEAP1NTSR2 | |
| SCHEMBL31679411 | 0.93 | NTSR1 (0.53) | MAPK8MAPK9MAPK10NTSR2NTSR1 | |
| SCHEMBL31679423 | 0.91 | AGTR2 (0.51) | MAPK8MAPK9MAPK10NTSR2NTSR1 | |
| SCHEMBL31679416 | 0.90 | MAPK8 (0.55) | MAPK8MAPK9MAPK10NTSR2NTSR1 | |
| SCHEMBL31679451 | 0.89 | AGTR2 (0.52) | MAPK8MAPK9MAPK10NTSR2NTSR1 | |
| SCHEMBL31679475 | 0.89 | MAPK8 (0.56) | MAPK8MAPK9MAPK10KEAP1NTSR2 | |
| SCHEMBL31679462 | 0.89 | AGTR2 (0.52) | MAPK8MAPK9MAPK10NTSR2NTSR1 | |
| SCHEMBL31679344 | 0.89 | NTSR1 (0.60) | MAPK8MAPK9MAPK10NTSR2NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4610269-A1 | UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR (UPAR) LIGANDS FOR DIAGNOSTIC OR THERAPEUTIC USE | 3B Pharmaceuticals GmbH (DE) | 2025-09-03 | — | — | EP | disclosed |