Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 5/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 5/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876221 | 1.00 | LMNA (0.53) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL31679940 | 0.88 | LMNA (0.65) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL31679861 | 0.86 | THRB (0.55) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876341 | 0.86 | THRB (0.55) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876202 | 0.86 | LMNA (0.51) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL31680002 | 0.86 | LMNA (0.51) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL31679997 | 0.84 | LMNA (0.57) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876257 | 0.81 | LMNA (0.54) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL31680057 | 0.81 | LMNA (0.54) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL31679858 | 0.80 | LMNA (0.65) | LMNAMEN1KMT2APKMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-B1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |