Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15943179 | 1.00 | ADRB2 (0.55) | ADRB2ADRB1AOC3CYP2D6NFKB1 | |
| SCHEMBL504837 | 1.00 | ADRB2 (0.55) | ADRB2ADRB1AOC3CYP2D6NFKB1 | |
| SCHEMBL342944 | 1.00 | ADRB2 (0.55) | ADRB2ADRB1AOC3CYP2D6NFKB1 | |
| SCHEMBL29633572 | 1.00 | ADRB2 (0.55) | ADRB2ADRB1AOC3CYP2D6NFKB1 | |
| SCHEMBL11743000 | 0.88 | ADRB2 (0.46) | ADRB2ADRB1AOC3CYP2D6NFKB1 | |
| SCHEMBL11606505 | 0.81 | TSHR (0.50) | ADRB2ADRB1AOC3CYP2D6NFKB1 | |
| SCHEMBL253300 | 0.81 | ADRB2 (0.52) | ADRB2ADRB1AOC3CYP2D6NFKB1 | |
| SCHEMBL253784 | 0.81 | ADRB2 (0.52) | ADRB2ADRB1AOC3CYP2D6NFKB1 | |
| SCHEMBL253722 | 0.81 | ADRB2 (0.52) | ADRB2ADRB1AOC3CYP2D6NFKB1 | |
| SCHEMBL253301 | 0.81 | ADRB2 (0.52) | ADRB2ADRB1AOC3CYP2D6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108410830-B | Ketoreductase and method for preparing (S) -1- (2-chlorphenyl) ethanol by catalyzing ketoreductase | 尚科生物医药（上海）有限公司 | 2021-06-25 | — | — | CN | claimed |
| WO-2025096957-A1 | RAS-PI3K INHIBITORS AND USES THEREOF | VIVIDION THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| US-12281058-B2 | Manganese catalysts and their use in hydrogenation of ketones | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2025-04-22 | — | — | US | disclosed |
| CN-119776301-A | Alcohol dehydrogenase, recombinant genetically engineered bacterium and application thereof in asymmetric reduction of potential chiral carbonyl compounds | 杭州文德阶生物科技有限公司 | 2025-04-08 | — | — | CN | disclosed |
| US-20240174683-A1 | MAP4K1 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-05-30 | — | — | US | disclosed |
| EP-4288437-A1 | MAP4K1 INHIBITORS | Bayer Aktiengesellschaft (DE) | 2023-12-13 | — | — | EP | disclosed |
| CN-113846082-B | Halohydrin dehalogenase mutant, encoding gene, recombinant vector, recombinant genetic engineering bacteria and application thereof | 华东理工大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-115209993-A | Catalyst comprising activated carbon having ruthenium complex adsorbed thereon and method for producing reduced product using same | 高砂香料工业株式会社 | 2022-10-18 | — | — | CN | disclosed |
| US-11427552-B2 | Heterocyclic compounds useful in the treatment of disease | EPIGEN BIOSCIENCES, INC. (US) | 2022-08-30 | — | — | US | disclosed |
| WO-2022167627-A1 | MAP4K1 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-08-11 | — | — | WO | disclosed |
| WO-2007030359-A1 | BENZIMIDAZOLE THIOPHENE COMPOUNDS AS PLK MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-15 | — | — | WO | disclosed |
| EP-1747224-A1 | COMPLEXES OF RUTHENIUM WITH 2-(AMINOMETHYL)PYRIDINES AND PHOSPHINES, THEIR PREPARATION AND USE AS CATALYSTS | Universita' Degli Studi di Udine (IT) | 2007-01-31 | — | — | EP | disclosed |
| US-20060035885-A1 | 8-Substituted-6,7,8,9-tetrahydropyrimido [1,2-a] pyrimidin-4-one derivatives | SANOFI-AVENTIS (FR) | 2006-02-16 | — | — | US | disclosed |
| EP-1608654-A2 | 8-SUBSTITUTED-6, 7, 8,9-TETRAHY9DROPYRIMIDO (1,2- a) PYRIMIDIN-4-ONE DERIVATIVES | Sanofi-Aventis (FR) | 2005-12-28 | — | — | EP | disclosed |
| WO-2005105819-A1 | COMPLEXES OF RUTHENIUM WITH 2-(AMINOMETHYL)PYRIDINES AND PHOSPHINES, THEIR PREPARATION AND USE AS CATALYSTS | UNIVERSITA' DEGLI STUDI DI UDINE (IT) | 2005-11-10 | — | — | WO | disclosed |
| CN-1174103-C | Process for preparing chiral substituted arylepoxyethane compounds and its biol by selective splitting of Aspergillus niger | 中国科学院上海有机化学研究所 | 2004-11-03 | — | — | CN | disclosed |
| WO-2004082577-A2 | 8-SUBSTITUTED-6, 7, 8, 9-TETRAHYDROPYRIMIDO[1,2-a] PYRIMIDIN-4-ONE DERIVATIVES | SANOFI-AVENTIS (FR) | 2004-09-30 | — | — | WO | disclosed |
| WO-2002069895-A2 | HETEROCYCLIC ANALGESIC COMPOUNDS AND METHODS OF USE THEREOF | SEPRACOR, INC. (US) | 2002-09-12 | — | — | WO | disclosed |
| EP-0198440-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 2-HALO-1-PHENYL ETHANOL | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-08-26 | — | — | EP | disclosed |
| US-4857468-A | BIOSYNTHESIS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12281058-B2 | Manganese catalysts and their use in hydrogenation of ketones | CYC1, SCO2, MT-CO3 | ADRB2 2518/4885ADRB1 2746/4885AOC3 91/4885 |
| US-20240174683-A1 | MAP4K1 INHIBITORS | MAP3K4, MAP4K4, MAP4K1 | ADRB2 3213/4885ADRB1 2123/4885AOC3 4395/4885 |
| US-11427552-B2 | Heterocyclic compounds useful in the treatment of disease | LPAR1, LPAR4, LPAR3 | ADRB2 357/4885ADRB1 247/4885AOC3 1647/4885 |
| US-20060035885-A1 | 8-Substituted-6,7,8,9-tetrahydropyrimido [1,2-a] pyrimidin-4-one derivatives | GSK3A, PSEN1, GSK3B | ADRB2 1284/4885ADRB1 644/4885AOC3 3463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.