Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316799 | 1.00 | ADRB2 (0.55) | ADRB2ADRB1AOC3CYP2D6NFKB1 | |
| SCHEMBL15943179 | 1.00 | ADRB2 (0.55) | ADRB2ADRB1AOC3CYP2D6NFKB1 | |
| SCHEMBL504837 | 1.00 | ADRB2 (0.55) | ADRB2ADRB1AOC3CYP2D6NFKB1 | |
| SCHEMBL29633572 | 1.00 | ADRB2 (0.55) | ADRB2ADRB1AOC3CYP2D6NFKB1 | |
| SCHEMBL11743000 | 0.88 | ADRB2 (0.46) | ADRB2ADRB1AOC3CYP2D6NFKB1 | |
| SCHEMBL11606505 | 0.81 | TSHR (0.50) | ADRB2ADRB1AOC3CYP2D6NFKB1 | |
| SCHEMBL253300 | 0.81 | ADRB2 (0.52) | ADRB2ADRB1AOC3CYP2D6NFKB1 | |
| SCHEMBL253784 | 0.81 | ADRB2 (0.52) | ADRB2ADRB1AOC3CYP2D6NFKB1 | |
| SCHEMBL253722 | 0.81 | ADRB2 (0.52) | ADRB2ADRB1AOC3CYP2D6NFKB1 | |
| SCHEMBL253301 | 0.81 | ADRB2 (0.52) | ADRB2ADRB1AOC3CYP2D6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117025581-A | Double-enzyme ordered immobilization method, product and application thereof | 杭州师范大学 | 2023-11-10 | — | — | CN | claimed |
| CN-115011574-A | Preparation method and application of site-controllable and ordered cross-linked double-enzyme aggregate | 杭州师范大学 | 2022-09-06 | — | — | CN | claimed |
| CN-104402661-A | Economic and efficient method for asymmetric synthesis of R-configuration aromatic alcohol through copper salt catalysis | UNIV JIANGNAN | 2015-03-11 | — | — | CN | claimed |
| CN-104388518-A | Preparation method of R-1-(2-chlorophenyl)ethanol and its ester | WANG TONGJUN | 2015-03-04 | — | — | CN | claimed |
| US-12454530-B2 | Amido cyclohexane acid derivatives as LPA receptor inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-10-28 | — | — | US | disclosed |
| US-20250304554-A1 | LPA RECEPTOR ANTAGONISTS AND USES THEREOF | GILEAD SCIENCES, INC. | 2025-10-02 | — | — | US | disclosed |
| US-12428430-B2 | Oxabicyclo acids as LPA antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-09-30 | — | — | US | disclosed |
| US-12338203-B2 | Urea compound for antagonizing LPA1 receptor | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2025-06-24 | — | — | US | disclosed |
| US-20250188068-A1 | AMIDO CYCLOPROPYL DERIVATIVES AS LPA RECEPTOR INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-06-12 | — | — | US | disclosed |
| US-20250066341-A1 | CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-02-27 | — | — | US | disclosed |
| WO-2025026266-A1 | COMPOUND AS LPAR1 ANTAGONIST, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 武汉朗来科技发展有限公司 | 2025-02-06 | — | — | WO | disclosed |
| US-12139474-B2 | LPA receptor antagonists and uses thereof | GILEAD SCIENCES, INC. (US) | 2024-11-12 | — | — | US | disclosed |
| US-20090170911-A1 | NOVEL AZOLE COMPOUND | AJINOMOTO CO. INC (JP) | 2009-07-02 | — | — | US | disclosed |
| US-20090105498-A1 | IMPROVED PROCESS FOR PREPARING 2-(SUBSTITUTED PHENYOL)-2-HYDROXY-ETHYL-CARBAMATES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-04-23 | — | — | US | disclosed |
| US-7517996-B2 | Azole compound | AJINOMOTO CO., INC. (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20080234525-A1 | Ruthenium/iridium complexes; hydrogenation catalysts | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2008-09-25 | — | — | US | disclosed |
| US-20060194850-A1 | Novel azole compound | AJINOMOTO CO. INC (JP) | 2006-08-31 | — | — | US | disclosed |
| WO-2002069895-A2 | HETEROCYCLIC ANALGESIC COMPOUNDS AND METHODS OF USE THEREOF | SEPRACOR, INC. (US) | 2002-09-12 | — | — | WO | disclosed |
| EP-0198440-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 2-HALO-1-PHENYL ETHANOL | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-08-26 | — | — | EP | disclosed |
| US-4857468-A | BIOSYNTHESIS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12338203-B2 | Urea compound for antagonizing LPA1 receptor | LPAR1, LPAR2, LPAR3 | ADRB2 308/4885ADRB1 72/4885AOC3 1368/4885 |
| US-12454530-B2 | Amido cyclohexane acid derivatives as LPA receptor inhibitors | LPAR1, LPAR2, LPAR3 | ADRB2 359/4885ADRB1 168/4885AOC3 1074/4885 |
| US-20090170911-A1 | NOVEL AZOLE COMPOUND | LPAR1, LPAR2, LPAR3 | ADRB2 486/4885ADRB1 324/4885AOC3 1165/4885 |
| US-12139474-B2 | LPA receptor antagonists and uses thereof | LPAR1, LPAR2, LPAR4 | ADRB2 842/4885ADRB1 440/4885AOC3 2383/4885 |
| US-12428430-B2 | Oxabicyclo acids as LPA antagonists | LPAR1, LPAR2, LPAR3 | ADRB2 132/4885ADRB1 66/4885AOC3 677/4885 |
| US-20090105498-A1 | IMPROVED PROCESS FOR PREPARING 2-(SUBSTITUTED PHENYOL)-2-HYDROXY-ETHYL-CARBAMATES | EPM2A, PYGB, KDM1B | ADRB2 3003/4885ADRB1 3791/4885AOC3 2638/4885 |
| US-20080234525-A1 | Ruthenium/iridium complexes; hydrogenation catalysts | ADH5, ADH1A, ADH1C | ADRB2 1405/4885ADRB1 1344/4885AOC3 1743/4885 |
| US-20250066341-A1 | CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS | LPAR1, LPAR2, LPAR3 | ADRB2 311/4885ADRB1 130/4885AOC3 1234/4885 |
| US-20250188068-A1 | AMIDO CYCLOPROPYL DERIVATIVES AS LPA RECEPTOR INHIBITORS | LPAR1, LPAR2, LPAR3 | ADRB2 569/4885ADRB1 238/4885AOC3 1754/4885 |
| US-20060194850-A1 | Novel azole compound | LPAR1, LPAR2, LPAR3 | ADRB2 486/4885ADRB1 324/4885AOC3 1165/4885 |
| US-20250304554-A1 | LPA RECEPTOR ANTAGONISTS AND USES THEREOF | LPAR1, LPAR2, LPAR4 | ADRB2 829/4885ADRB1 442/4885AOC3 2638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.