Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31679948 | 0.86 | MEN1 (0.63) | THRBPOLBPKMGAAMEN1 | |
| SCHEMBL24876127 | 0.86 | MEN1 (0.63) | THRBPOLBPKMGAAMEN1 | |
| SCHEMBL31680001 | 0.84 | THRB (0.53) | THRBTP53POLBPKMGAA | |
| SCHEMBL24875967 | 0.84 | THRB (0.53) | THRBTP53POLBPKMGAA | |
| SCHEMBL31680036 | 0.82 | THRB (0.58) | THRBTP53POLBPKMGAA | |
| SCHEMBL24876213 | 0.82 | THRB (0.64) | THRBTP53POLBPKMGAA | |
| SCHEMBL31679812 | 0.82 | THRB (0.64) | THRBTP53POLBPKMGAA | |
| SCHEMBL24876125 | 0.81 | MOGAT2 (0.58) | THRBTP53POLBPKMGAA | |
| SCHEMBL24876134 | 0.79 | THRB (0.52) | THRBTP53POLBPKMGAA | |
| SCHEMBL24875965 | 0.75 | MAPT (0.53) | THRBTP53POLBPKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-B1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |