Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | PKM | P14618 | 5/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31679948 | 1.00 | MEN1 (0.63) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL31679995 | 0.86 | THRB (0.53) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL31307838 | 0.83 | MEN1 (0.67) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL23493830 | 0.83 | MEN1 (0.67) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL24876742 | 0.82 | PKM (0.76) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL24876039 | 0.82 | MEN1 (0.72) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL24876653 | 0.80 | LMNA (0.69) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL31680016 | 0.80 | LMNA (0.69) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL24876169 | 0.80 | MEN1 (0.72) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL24876741 | 0.80 | LMNA (0.76) | MEN1KMT2ALMNAPKMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |