Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | UQCRB | P14927 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876017 | 0.85 | MEN1 (0.70) | MEN1KMT2ABRD4LMNATHRB | |
| SCHEMBL31679837 | 0.84 | LMNA (0.58) | MEN1KMT2ABRD4LMNATHRB | |
| SCHEMBL24876113 | 0.81 | MEN1 (0.61) | MEN1KMT2ALMNATHRBPKM | |
| SCHEMBL24876209 | 0.80 | MAPT (0.52) | MEN1KMT2ALMNATHRBALDH1A1 | |
| SCHEMBL31679934 | 0.80 | MEN1 (0.47) | MEN1KMT2ALMNATHRBPKM | |
| SCHEMBL24876169 | 0.76 | MEN1 (0.72) | MEN1KMT2ALMNATHRBPKM | |
| SCHEMBL24876645 | 0.75 | THRB (0.76) | MEN1KMT2ALMNATHRBPKM | |
| SCHEMBL31680055 | 0.75 | THRB (0.76) | MEN1KMT2ALMNATHRBPKM | |
| SCHEMBL24876095 | 0.74 | LMNA (0.69) | MEN1KMT2ALMNATHRBPKM | |
| SCHEMBL24876665 | 0.74 | THRB (0.57) | MEN1KMT2ABRD4LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-B1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |