SCHEMBL31683751

SCHEMBL31683751

FC(F)=CCc1cccc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.47
CYP2C19 P33261 4/20 0.47
CYP1A2 P05177 3/20 0.47
CYP2C9 P11712 2/20 0.47
HPGD P15428 1/20 0.46
HTT P42858 1/20 0.46
ACP3 P15309 1/20 0.46
CYP2D6 P10635 2/20 0.44
CTNNB1 P35222 1/20 0.44
CYP3A4 P08684 2/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
MTNR1A P48039 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10049304 1.00 TDP1 (0.47) TDP1CYP2C19CYP1A2CYP2C9HPGD
SCHEMBL11792152 0.82 TDP1 (0.53) TDP1CYP2C19CYP1A2CYP2C9HPGD
SCHEMBL10049308 0.81 MTNR1A (0.45) TDP1CYP2C19CYP1A2CYP2C9HPGD
SCHEMBL3682565 0.81 XPO1 (0.51) TDP1CYP2C19CYP1A2CYP2C9HPGD
SCHEMBL10049310 0.79 MTNR1A (0.44) TDP1CYP2C19CYP1A2CYP2C9ACP3
SCHEMBL6411524 0.78 CYP1A2 (0.52) TDP1CYP2C19CYP1A2CYP2C9HPGD
SCHEMBL8378939 0.78 CYP2C19 (0.52) TDP1CYP2C19CYP1A2CYP2C9HPGD
SCHEMBL5830944 0.77 CYP2C19 (0.56) TDP1CYP2C19CYP1A2CYP2C9HPGD
Naphthalen-1-Yl-Methanol SCHEMBL28403 0.77 CYP1A2 (0.60) TDP1CYP2C19CYP1A2CYP2C9HPGD
Hydrogen Sulfide SCHEMBL28143945 0.76 CYP1A2 (0.50) TDP1CYP2C19CYP1A2CYP2C9HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120623023-A Dihydronaphthalene compound with monofluorinated conjugated diene structure and preparation and application thereof 上海大学 2025-09-12 CN disclosed