Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 2/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | PAK4 | O96013 | 2/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | AKT2 | P31751 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.49 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.49 |
| ▸ | PRKX | P51817 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28658687 | 1.00 | TACR3 (0.53) | TACR3ROCK2MAPK1PAK4MAPK13 | |
| SCHEMBL31683869 | 0.82 | TACR3 (0.50) | TACR3ALDH1A1RAB9AL3MBTL1KDM4E | |
| SCHEMBL31683867 | 0.82 | TACR3 (0.50) | TACR3ALDH1A1RAB9AL3MBTL1KDM4E | |
| SCHEMBL25406277 | 0.82 | TACR3 (0.51) | TACR3ROCK2MAPK1PAK4MAPK13 | |
| SCHEMBL30254951 | 0.82 | TACR3 (0.51) | TACR3ROCK2MAPK1PAK4MAPK13 | |
| SCHEMBL28664069 | 0.81 | ROCK2 (0.52) | ROCK2MAPK1RPS6KA5PRKACARPS6KB1 | |
| SCHEMBL31622393 | 0.81 | ROCK2 (0.52) | ROCK2MAPK1RPS6KA5PRKACARPS6KB1 | |
| SCHEMBL5643849 | 0.79 | NPC1 (0.55) | TACR3ROCK2MAPK1PAK4MAPK13 | |
| SCHEMBL25407128 | 0.75 | ROCK2 (0.57) | TACR3ROCK2MAPK1PAK4MAPK13 | |
| SCHEMBL30040770 | 0.74 | TACR3 (0.64) | TACR3ROCK2MAPK1PAK4MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12414565-B2 | Pyridazine (THIO)amides as fungicidal compounds | BAYER AKTIENGESELLSCHAFT (DE) | 2025-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12414565-B2 | Pyridazine (THIO)amides as fungicidal compounds | PNPO, TPMT, BLVRB | TACR3 196/4885ROCK2 3779/4885MAPK1 3000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.