SCHEMBL31684301

SCHEMBL31684301

COc1ccc(CNc2nccc3c2c(Nc2cnn(C4CC4)c2)nn3[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c(OC)c1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MET P08581 1/20 0.40
▸ BTK Q06187 4/20 0.38
▸ JAK3 P52333 6/20 0.37
▸ EGFR P00533 1/20 0.37
▸ LCK P06239 1/20 0.37
▸ PDE9A O76083 2/20 0.37
▸ MAPT P10636 1/20 0.36
▸ KDR P35968 2/20 0.36
▸ CSF1R P07333 1/20 0.36
▸ PDGFRB P09619 1/20 0.36
▸ JAK2 O60674 2/20 0.36
▸ KLKB1 P03952 1/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ FGFR3 P22607 1/20 0.35
▸ JAK1 P23458 1/20 0.35
▸ TYK2 P29597 1/20 0.35
▸ DDB1 Q16531 1/20 0.35
▸ CRBN Q96SW2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20645517 1.00 MET (0.40) METBTKJAK3EGFRLCK
SCHEMBL22009438 0.94 JAK3 (0.37) METBTKJAK3EGFRLCK
SCHEMBL21903611 0.92 KMT2A (0.39) BTKJAK3PDE9AKDRCSF1R
SCHEMBL21903606 0.92 KMT2A (0.39) BTKJAK3PDE9AKDRCSF1R
SCHEMBL20645567 0.86 BTK (0.41) BTKPDE9AMAPTKMT2A
SCHEMBL31125791 0.85 BTK (0.41) BTKEGFRPDE9AMAPTKMT2A
SCHEMBL31684304 0.85 BTK (0.41) BTKPDE9AMAPTKMT2A
SCHEMBL15913950 0.85 BTK (0.41) BTKPDE9AMAPTKMT2A
SCHEMBL31684324 0.85 BTK (0.41) BTKPDE9AMAPTKMT2A
SCHEMBL25649309 0.85 BTK (0.41) BTKEGFRPDE9AMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3653626-B1 NOVEL 1H-PYRAZOLOPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME DAEWOONG PHARMACEUTICAL CO LTD (KR) 2025-09-17 — — EP disclosed
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