SCHEMBL316852

SCHEMBL316852

CC1(C)CC(c2ccc(C(=O)O)c(C3CC(C)(C)N(O)C(C)(C)C3)c2C(=O)O)CC(C)(C)N1O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.35
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 1/20 0.35
ALOX15 P16050 1/20 0.35
HAAO P46952 1/20 0.34
HTT P42858 1/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17838616 0.95 GAA (0.32) GAAKDM4EALDH1A1ALOX15HAAO
SCHEMBL317241 0.90 GAA (0.34) GAAKDM4EALDH1A1ALOX15HAAO
SCHEMBL11164595 0.89 METAP2 (0.36)
SCHEMBL316278 0.88 HAAO (0.40) GAAKDM4EALDH1A1ALOX15HAAO
SCHEMBL9739312 0.86 TSHR (0.33) KDM4EALDH1A1KMT2AMAPT
SCHEMBL7191505 0.85 GAA (0.39) GAAKDM4EALDH1A1ALOX15HAAO
SCHEMBL10576256 0.85 KDM4E (0.30) KDM4E
SCHEMBL8148845 0.84 KDM4E (0.37) GAAKDM4EALDH1A1ALOX15HTT
SCHEMBL4011708 0.83 ALOX15 (0.41) GAAKDM4EALOX15HTTKMT2A
SCHEMBL9737841 0.83 TSHR (0.46) GAAALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180346834-A1 COAL DUST TREATMENT METHODS AND COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2018-12-06 US claimed
EP-3303525-A2 COAL DUST TREATMENT METHODS AND COMPOSITIONS General Electric Company (US) 2018-04-11 EP claimed
EP-2876099-B1 Norbornadiene purification method AIR LIQUIDE (FR) 2017-11-15 EP claimed
WO-2016191019-A2 COAL DUST TREATMENT METHODS AND COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2016-12-01 WO claimed
EP-2876098-B1 Extractive distillation in a norbornadiene purification method AIR LIQUIDE (FR) 2016-07-13 EP claimed
WO-2015074874-A1 EXTRACTIVE DISTILLATION IN A NORBORNADIENE PURIFICATION METHOD L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2015-05-28 WO claimed
WO-2015074875-A1 NORBORNADIENE PURIFICATION METHOD L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2015-05-28 WO claimed
EP-2876098-A1 Extractive distillation in a norbornadiene purification method L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2015-05-27 EP claimed
EP-2876099-A1 Norbornadiene purification method L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2015-05-27 EP claimed
US-8618224-B2 Viscosity breaking process for olefin polymers BASF SE (DE) 2013-12-31 US claimed
EP-0963971-B1 Method for inhibiting polymer formation in styrene processing NALCO EXXON ENERGY CHEM LP (US) 2001-11-07 EP claimed
WO-2001040404-A1 COMPOSITION AND METHOD FOR INHIBITING POLYMERIZATION AND POLYMER GROWTH UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-06-07 WO claimed
EP-0703220-B1 Process for the preparation of N-oxyl hindered amine esters using tetraalkyl orthotitanate tranesterification catalysts CIBA SC HOLDING AG (CH) 2001-01-03 EP claimed
EP-0794933-B1 A METHOD FOR INHIBITING PREMATURE POLYMERIZATION OF VINYL AROMATIC MONOMERS CIBA SC HOLDING AG (CH) 2000-01-05 EP claimed
US-5711767-A AMINES, PHENOLIC COMPOUNDS AND NITROXIDE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-01-27 US claimed
EP-0581737-B1 Inhibiting polymerization of vinyl aromatic monomers CIBA GEIGY AG (CH) 1997-04-23 EP claimed
US-5545782-A USING A STABLE HINDERED NITROXYL COMPOUND CIBA-GEIGY CORPORATION (US) 1996-08-13 US claimed
EP-0309401-B1 Stabilization of coatings with N-hydroxy hindered amines CIBA GEIGY AG (CH) 1994-10-26 EP claimed
US-5064883-A Stabilization of acid catalyzed thermoset resins with n-hydroxy hindered amines CIBA-GEIGY CORPORATION (US) 1991-11-12 US claimed
US-5006577-A Durable, weatherproof CIBA-GEIGY CORPORATION (US) 1991-04-09 US claimed