Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10384781 | 0.85 | ALDH1A1 (0.48) | PADI4CYP1A2ALDH1A1TSHRERN1 | |
| SCHEMBL3268264 | 0.84 | HTT (0.57) | PADI4ERN1MAPTKDM4ELMNA | |
| SCHEMBL3268788 | 0.84 | PADI4 (0.42) | PADI4CYP1A2ALDH1A1TSHRERN1 | |
| SCHEMBL3269246 | 0.84 | ALDH1A1 (0.43) | PADI4CYP1A2ALDH1A1TSHRERN1 | |
| SCHEMBL3267563 | 0.84 | PADI4 (0.42) | PADI4CYP1A2ALDH1A1TSHRERN1 | |
| SCHEMBL9839130 | 0.82 | MAPT (0.44) | PADI4CYP1A2ALDH1A1TSHRERN1 | |
| SCHEMBL12521593 | 0.82 | PADI4 (0.41) | PADI4CYP1A2ALDH1A1TSHRERN1 | |
| SCHEMBL11302952 | 0.82 | PADI4 (0.48) | PADI4CYP1A2ALDH1A1TSHRERN1 | |
| SCHEMBL15922323 | 0.81 | PADI4 (0.53) | PADI4CYP1A2ALDH1A1ERN1MAPT | |
| SCHEMBL9838932 | 0.81 | PADI4 (0.44) | PADI4CYP1A2ALDH1A1TSHRERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331710-A1 | HETEROCYCLIC COMPOUND, PREPARATION METHOD AND USE THEREOF | SHANGHAI MEIYUE BIOTECH DEVELOPMENT CO. LTD (CN) | 2023-10-19 | — | — | US | disclosed |
| US-20230331710-A1 | HETEROCYCLIC COMPOUND, PREPARATION METHOD AND USE THEREOF | SHANGHAI MEIYUE BIOTECH DEVELOPMENT CO. LTD (CN) | 2023-10-19 | — | — | US | disclosed |
| EP-4194449-A1 | HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Meiyue Biotech Development Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |
| US-20200131144-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | PHENEX-FXR GMBH (DE) | 2020-04-30 | — | — | US | disclosed |
| WO-2019016269-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | PHENEX-FXR GMBH (DE) | 2019-01-24 | — | — | WO | disclosed |
| US-8911837-B2 | Retardation film, optical laminated body, liquid crystal panel, and liquid crystal display | NITTO DENKO CORPORATION (JP) | 2014-12-16 | — | — | US | disclosed |
| CN-101512402-B | Phase difference film, optical laminate, liquid crystal panel, and liquid crystal display device | NITTO DENKO CORP | 2012-04-04 | — | — | CN | disclosed |
| EP-1914229-B1 | NOVEL CERCOSPORAMIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-06-16 | — | — | EP | disclosed |
| US-7643118-B2 | Liquid crystal panel and liquid crystal display device | NITTO DENKO CORPORATION (JP) | 2010-01-05 | — | — | US | disclosed |
| CN-101512402-A | Phase difference film, optical laminate, liquid crystal panel, and liquid crystal display device | NITTO DENKO CORP (JP) | 2009-08-19 | — | — | CN | disclosed |
| US-20090167999-A1 | RETARDATION FILM, OPTICAL LAMINATED BODY, LIQUID CRYSTAL PANEL, AND LIQUID CRYSTAL DISPLAY | NITTO DENKO CORPORATION (JP) | 2009-07-02 | — | — | US | disclosed |
| US-20090109385-A1 | LIQUID CRYSTAL PANEL AND LIQUID CRYSTAL DISPLAY DEVICE | NITTO DENKO CORPORATION (JP) | 2009-04-30 | — | — | US | disclosed |
| US-20090036492-A1 | Novel Cercosporamide Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-02-05 | — | — | US | disclosed |
| CN-101326461-A | Liquid crystal panel and liquid crystal display device | NITTO DENKO CORP (JP) | 2008-12-17 | — | — | CN | disclosed |
| EP-1914229-A1 | NOVEL CERCOSPORAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| EP-0124992-B1 | HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES | ICI AUSTRALIA LIMITED (AU) | 1991-05-29 | — | — | EP | disclosed |
| US-4680400-A | Herbicidal cyclohexane-1,3-dione-5-isoquinoline derivatives | ICI AUSTRALIA LIMITED (AU) | 1987-07-14 | — | — | US | disclosed |
| US-4640708-A | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1987-02-03 | — | — | US | disclosed |
| EP-0124992-A1 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1984-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331710-A1 | HETEROCYCLIC COMPOUND, PREPARATION METHOD AND USE THEREOF | C9, CFB, C5 | PADI4 2514/4885CYP1A2 286/4885ALDH1A1 3003/4885 |
| US-20090036492-A1 | Novel Cercosporamide Derivative | GPR119, CBR3, SLC5A2 | PADI4 3251/4885CYP1A2 972/4885ALDH1A1 381/4885 |
| US-20200131144-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | NR1H2, NR1H3, NR1H4 | PADI4 3743/4885CYP1A2 292/4885ALDH1A1 2016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.