SCHEMBL31686488

CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)N)C(C)C)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCCNC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)O)C(C)C

nearest known ligand 0.53

Predicted protein targets (top 17)

	gene	UniProt	supporting neighbours	confidence
▸	RAMP3	O60896	4/20	0.53

▸	CALCR	P30988	4/20	0.53

▸	EPHA2	P29317	2/20	0.51

▸	CALCRL	Q16602	1/20	0.49

▸	NPY2R	P49146	5/20	0.48

▸	NPY4R	P50391	5/20	0.48

▸	NPY5R	Q15761	5/20	0.48

▸	NPY1R	P25929	3/20	0.48

▸	ABCB11	O95342	1/20	0.48

▸	KISS1R	Q969F8	3/20	0.48

▸	DRD1	P21728	1/20	0.48

▸	GNRHR	P30968	1/20	0.48

▸	OPRM1	P35372	1/20	0.48

▸	MRGPRX2	Q96LB1	1/20	0.48

▸	NTSR2	O95665	1/20	0.47

▸	NTSR1	P30989	1/20	0.47

▸	SORT1	Q99523	1/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31686489	0.96	EPHA2 (0.51)	RAMP3CALCREPHA2CALCRLNPY2R
SCHEMBL30293724	0.86	NPY4R (0.56)	EPHA2NPY2RNPY4RNPY5RNPY1R
SCHEMBL30015129	0.82	SLC6A2 (0.51)	CALCRLNPY2RNPY4RNPY5RNPY1R
SCHEMBL31307275	0.82	RAMP3 (0.62)	RAMP3CALCREPHA2NPY2RNPY4R
SCHEMBL30974464	0.82	SLC6A2 (0.58)	RAMP3CALCRCALCRLNTSR2NTSR1
SCHEMBL31307280	0.81	RAMP3 (0.60)	RAMP3CALCREPHA2NPY2RNPY4R
SCHEMBL31683488	0.81	RAMP3 (0.69)	RAMP3CALCREPHA2NPY2RNPY4R
SCHEMBL30726587	0.81	RAMP3 (0.61)	RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL29396082	0.80	RAMP3 (0.64)	RAMP3CALCREPHA2NPY2RNPY4R
SCHEMBL29390426	0.80	OPRM1 (0.61)	RAMP3CALCREPHA2NPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12421302-B2	CAR-t cells and autoimmune diseases	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US)	2025-09-23	—	—	US	disclosed