SCHEMBL31691244

SCHEMBL31691244

COc1ccc(C(C)(C)C)nc1S(=O)(=O)NC(=O)c1ccc(Cn2ccc(N)n2)c(OC)n1

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ TRPV1 Q8NER1 1/20 0.33
▸ FLT3 P36888 1/20 0.32
▸ IRAK4 Q9NWZ3 1/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ LMNA P02545 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ PTGS1 P23219 1/20 0.32
▸ PTGS2 P35354 1/20 0.32
▸ CSF1R P07333 1/20 0.32
▸ MEN1 O00255 3/20 0.31
▸ KMT2A Q03164 3/20 0.31
▸ NPC1 O15118 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ POLB P06746 1/20 0.31
▸ PKM P14618 1/20 0.30
▸ CA1 P00915 1/20 0.30
▸ CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31691476 0.86 RXFP1 (0.35) TRPV1FLT3IRAK4ALDH1A1LMNA
SCHEMBL31691304 0.86 KAT7 (0.38) —
SCHEMBL31691361 0.81 KAT7 (0.36) —
SCHEMBL31691325 0.81 KAT7 (0.34) —
SCHEMBL31691277 0.80 KAT7 (0.38) TRPV1
SCHEMBL31691260 0.78 KAT7 (0.37) —
SCHEMBL31691372 0.76 HTT (0.39) ALDH1A1
SCHEMBL31691405 0.75 KAT7 (0.39) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL31691424 0.72 KLKB1 (0.42) ALDH1A1SMN1; SMN2MEN1KMT2APOLB
SCHEMBL31691398 0.71 KAT7 (0.43) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304535-A1 KAT6 Inhibitors BEIGENE SWITZERLAND GMBH (CH) 2025-10-02 — — US disclosed
WO-2025201504-A1 KAT6 INHIBITORS BEIGENE (SUZHOU) CO., LTD. (CN) 2025-10-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304535-A1 KAT6 Inhibitors KAT6A, KAT6B, KAT2A TRPV1 4211/4885FLT3 4615/4885IRAK4 2757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback