SCHEMBL31691476

SCHEMBL31691476

COc1ccc(C(C)(C)C)nc1S(=O)(=O)NC(=O)c1ccc(Cn2ccc(NC(=O)OC(C)(C)C)n2)c(OC)n1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RXFP1 Q9HBX9 1/20 0.35
▸ CACNA1G O43497 1/20 0.33
▸ CACNA1H O95180 1/20 0.33
▸ CACNA1I Q9P0X4 1/20 0.33
▸ CPT1A P50416 7/20 0.32
▸ CPT1B Q92523 7/20 0.32
▸ GNRHR P30968 1/20 0.32
▸ LMNA P02545 4/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ TRPV1 Q8NER1 1/20 0.31
▸ PTGER1 P34995 1/20 0.30
▸ FLT3 P36888 1/20 0.30
▸ IRAK4 Q9NWZ3 1/20 0.30
▸ KDM4E B2RXH2 1/20 0.30
▸ TP53 P04637 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31691244 0.86 TRPV1 (0.33) LMNAKMT2AALDH1A1MAPK1SMN1; SMN2
SCHEMBL31691304 0.82 KAT7 (0.38) —
SCHEMBL31691255 0.79 KMT2A (0.41) RXFP1CACNA1GCACNA1HCACNA1ILMNA
SCHEMBL31691335 0.79 CACNA1G (0.39) CACNA1GCACNA1HCACNA1ILMNAKMT2A
SCHEMBL31691325 0.78 KAT7 (0.34) —
SCHEMBL31691361 0.78 KAT7 (0.36) —
SCHEMBL31691277 0.77 KAT7 (0.38) TRPV1
SCHEMBL31691260 0.74 KAT7 (0.37) —
SCHEMBL31691372 0.73 HTT (0.39) ALDH1A1
SCHEMBL31556383 0.72 MAP3K5 (0.36) RXFP1LMNAKMT2AKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304535-A1 KAT6 Inhibitors BEIGENE SWITZERLAND GMBH (CH) 2025-10-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304535-A1 KAT6 Inhibitors KAT6A, KAT6B, KAT2A RXFP1 3280/4885CACNA1G 3349/4885CACNA1H 3550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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