SCHEMBL31691402

SCHEMBL31691402

COc1ccc(C(C)(C)C)cc1S(=O)(=O)NC(=O)c1ccc(Cn2cccn2)c(C2CCO2)c1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KAT7 O95251 16/20 0.42
▸ KAT6A Q92794 16/20 0.42
▸ KAT6B Q8WYB5 10/20 0.42
▸ KAT5 Q92993 7/20 0.42
▸ KAT8 Q9H7Z6 7/20 0.42
▸ MEN1 O00255 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ NPSR1 Q6W5P4 2/20 0.38
▸ GAA P10253 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ KLKB1 P03952 1/20 0.38
▸ ALPL P05186 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31516741 0.92 KAT7 (0.46) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31691246 0.87 ALPL (0.43) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31691394 0.86 KAT7 (0.44) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31691431 0.86 KAT7 (0.45) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31516641 0.86 KAT7 (0.46) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31516707 0.85 KAT7 (0.48) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31691386 0.85 ALPL (0.41) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31516663 0.85 KAT7 (0.45) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31516723 0.84 KAT7 (0.44) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31172569 0.83 KAT7 (0.42) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304535-A1 KAT6 Inhibitors BEIGENE SWITZERLAND GMBH (CH) 2025-10-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304535-A1 KAT6 Inhibitors KAT6A, KAT6B, KAT2A KAT7 4/4885KAT6A 1/4885KAT6B 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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