Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.30 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.30 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.30 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254869 | 0.80 | ACHE (0.46) | CYP1A2ADORA2AADORA2BMAP2K4JAK2 | |
| SCHEMBL31539742 | 0.72 | CYP1A2 (0.53) | CYP1A2ADORA2AADORA2BMAP2K4JAK2 | |
| Furan SCHEMBL16857687 | 0.70 | CYP1A2 (0.44) | CYP1A2ADORA2AADORA2BMAP2K4JAK2 | |
| SCHEMBL29769133 | 0.69 | MAP2K4 (0.57) | CYP1A2ADORA2AADORA2BMAP2K4JAK2 | |
| SCHEMBL12222 | 0.69 | MAP2K4 (0.57) | CYP1A2ADORA2AADORA2BMAP2K4JAK2 | |
| SCHEMBL31692009 | 0.69 | ATM (0.48) | MAPK1 | |
| SCHEMBL130625 | 0.69 | CYP1A2 (0.70) | CYP1A2ADORA2AADORA2BIDO1LRRK2 | |
| SCHEMBL29557196 | 0.69 | CYP1A2 (0.70) | CYP1A2ADORA2AADORA2BIDO1LRRK2 | |
| SCHEMBL16417603 | 0.69 | ADORA2A (0.42) | CYP1A2ADORA2AADORA2B | |
| SCHEMBL1344802 | 0.68 | DYRK1A (0.43) | CYP1A2ADORA2AADORA2BMAP2K4JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | BIOGEN MA INC. | 2025-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | TYK2, JAK2, JAK1 | CYP1A2 2380/4885ADORA2A 3773/4885ADORA2B 3764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.