Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.30 |
| ▸ | NFATC1 | O95644 | 2/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3224448 | 0.80 | ATM (0.52) | ATMPIM1PIM3PIM2HTR6 | |
| SCHEMBL29535106 | 0.80 | ATM (0.52) | ATMPIM1PIM3PIM2HTR6 | |
| SCHEMBL31691968 | 0.69 | CYP1A2 (0.42) | MAPK1 | |
| SCHEMBL14438035 | 0.69 | ATM (0.46) | ATMPIM1PIM3PIM2PDE4A | |
| SCHEMBL2619228 | 0.68 | DYRK1A (0.56) | ATMPIM1PIM3PIM2HTR6 | |
| SCHEMBL3483408 | 0.67 | ATM (0.41) | ATMPIM1PIM3PIM2PDE4A | |
| SCHEMBL366553 | 0.66 | ATM (1.00) | ATMHTR6HTR1AHTR7IMPDH2 | |
| SCHEMBL5396 | 0.66 | ATM (1.00) | ATMHTR6HTR1AHTR7IMPDH2 | |
| SCHEMBL19015246 | 0.65 | ATM (0.39) | ATMPIM1PIM3PIM2PDE4A | |
| Ammonia Solution, Strong SCHEMBL9066277 | 0.64 | ATM (0.95) | ATMHTR6HTR1AHTR7IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | BIOGEN MA INC. | 2025-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | TYK2, JAK2, JAK1 | ATM 407/4885PIM1 248/4885PIM3 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.