Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2625477 | 1.00 | NUDT1 (0.42) | NUDT1LOXLOXL2MTNR1AMTNR1B | |
| SCHEMBL31691850 | 0.84 | NUDT1 (0.40) | NUDT1LOXLOXL2MTNR1AMTNR1B | |
| SCHEMBL2650433 | 0.84 | NUDT1 (0.40) | NUDT1LOXLOXL2MTNR1AMTNR1B | |
| SCHEMBL17117534 | 0.82 | MALT1 (0.42) | NUDT1LOXLOXL2MTNR1AMTNR1B | |
| SCHEMBL22550724 | 0.82 | NUDT1 (0.37) | NUDT1ADORA2AADORA1GAA | |
| SCHEMBL24714984 | 0.80 | NUDT1 (0.43) | NUDT1ADORA2AADORA1 | |
| SCHEMBL22624172 | 0.78 | NUDT1 (0.39) | NUDT1LOXLOXL2MTNR1AMTNR1B | |
| SCHEMBL24759681 | 0.77 | MTNR1A (0.42) | NUDT1MTNR1AMTNR1BPOLBTDP1 | |
| SCHEMBL24759324 | 0.77 | NUDT1 (0.41) | NUDT1LOXLOXL2MTNR1AMTNR1B | |
| SCHEMBL29159093 | 0.76 | SMN1; SMN2 (0.35) | NUDT1MTNR1AMTNR1BADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | BIOGEN MA INC. | 2025-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | TYK2, JAK2, JAK1 | NUDT1 4220/4885LOX 899/4885LOXL2 712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.