Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.33 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL450834 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KDM4EL3MBTL1KCNJ1CYP2A6 | |
| SCHEMBL18810226 | 0.76 | KDM4E (0.40) | ALDH1A1KDM4EL3MBTL1KCNJ1CYP2A6 | |
| SCHEMBL28713176 | 0.74 | P4HTM (0.58) | ALDH1A1KDM4EHSD17B10POLBSMN1; SMN2 | |
| SCHEMBL28713179 | 0.74 | P4HTM (0.58) | ALDH1A1KDM4EHSD17B10POLBSMN1; SMN2 | |
| SCHEMBL16287685 | 0.73 | KDM4E (0.38) | ALDH1A1KDM4EL3MBTL1KCNJ1CYP2A6 | |
| SCHEMBL30409880 | 0.73 | KDM4E (0.38) | ALDH1A1KDM4EL3MBTL1KCNJ1CYP2A6 | |
| SCHEMBL7992302 | 0.72 | ALDH1A1 (0.37) | ALDH1A1KDM4EL3MBTL1KCNJ1CYP2A6 | |
| SCHEMBL26001309 | 0.72 | KDM4E (0.37) | ALDH1A1KDM4EL3MBTL1KCNJ1CYP2A6 | |
| SCHEMBL29952230 | 0.71 | ALDH1A1 (0.31) | ALDH1A1KDM4EL3MBTL1KCNJ1 | |
| SCHEMBL19260339 | 0.71 | KDM4E (0.33) | ALDH1A1KDM4EL3MBTL1KCNJ1ALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3891149-B1 | RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2026-01-28 | — | — | EP | disclosed |
| US-20250214983-A1 | 1,3,4-OXADIAZOLE TRIAZOLE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2025-07-03 | — | — | US | disclosed |
| US-12312348-B2 | RET inhibitors, pharmaceutical compositions and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2025-05-27 | — | — | US | disclosed |
| EP-4554942-A1 | 1,3,4-OXADIAZOLE TRIAZOLE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2025-05-21 | — | — | EP | disclosed |
| CN-119451953-A | 1,3, 4-Oxadiazole triazole compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions containing the same | 株式会社 钟根堂 | 2025-02-14 | — | — | CN | disclosed |
| CN-111285873-B | RET inhibitor, pharmaceutical composition thereof and application thereof | 广东东阳光药业股份有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-111285874-B | RET inhibitor, pharmaceutical composition thereof and application thereof | 广东东阳光药业股份有限公司 | 2024-08-09 | — | — | CN | disclosed |
| EP-4392415-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS | Yuhan Corporation (KR) | 2024-07-03 | — | — | EP | disclosed |
| US-11981658-B2 | Substituted aminopyridine compounds as EGFR inhibitors | YUHAN CORPORATION (KR) | 2024-05-14 | — | — | US | disclosed |
| CN-117980297-A | Substituted aminopyridine compounds as EGFR inhibitors | 柳韩洋行 | 2024-05-03 | — | — | CN | disclosed |
| EP-2813495-A1 | 2-ARYLBENZOFURAN-7-FORMAMIDE COMPOUNDS, PREPARATION METHOD AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2014-12-17 | — | — | EP | disclosed |
| US-8715635-B2 | Frictionless molecular rotary motors | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2014-05-06 | — | — | US | disclosed |
| US-8715635-B2 | Frictionless molecular rotary motors | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2014-05-06 | — | — | US | disclosed |
| US-8715635-B2 | Frictionless molecular rotary motors | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2014-05-06 | — | — | US | disclosed |
| CN-103242273-A | 2-arylbenzofuran-7-methanamide compound, preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2013-08-14 | — | — | CN | disclosed |
| US-20100016610-A1 | FRICTIONLESS MOLECULAR ROTARY MOTORS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2010-01-21 | — | — | US | disclosed |
| US-20100016610-A1 | FRICTIONLESS MOLECULAR ROTARY MOTORS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2010-01-21 | — | — | US | disclosed |
| US-20100016610-A1 | FRICTIONLESS MOLECULAR ROTARY MOTORS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2010-01-21 | — | — | US | disclosed |
| WO-2008096360-A2 | FRICTIONLESS MOLECULAR ROTARY MOTORS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008096360-A2 | FRICTIONLESS MOLECULAR ROTARY MOTORS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2008-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250214983-A1 | 1,3,4-OXADIAZOLE TRIAZOLE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | HDAC6, HDAC1, HDAC3 | ALDH1A1 213/4885KDM4E 581/4885L3MBTL1 3867/4885 |
| US-11981658-B2 | Substituted aminopyridine compounds as EGFR inhibitors | EGFR, ERBB2, ERBB4 | ALDH1A1 2639/4885KDM4E 2715/4885L3MBTL1 3384/4885 |
| US-12312348-B2 | RET inhibitors, pharmaceutical compositions and uses thereof | RET, SLC10A2, REL | ALDH1A1 2416/4885KDM4E 3540/4885L3MBTL1 4535/4885 |
| US-20100016610-A1 | FRICTIONLESS MOLECULAR ROTARY MOTORS | DYNLL2, ATXN2L, DYNLL1 | ALDH1A1 3211/4885KDM4E 4205/4885L3MBTL1 2840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.