SCHEMBL31695290

SCHEMBL31695290

N#Cc1c(-c2ccc(O)c(O)c2)cc(-c2cccnc2)[nH]c1=N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MET P08581 1/20 0.48
▸ KDR P35968 1/20 0.48
▸ IKBKB O14920 1/20 0.45
▸ KDM4E B2RXH2 6/20 0.43
▸ GAA P10253 3/20 0.43
▸ GLA P06280 2/20 0.43
▸ CYP19A1 P11511 1/20 0.43
▸ ADORA2A P29274 1/20 0.41
▸ TDP1 Q9NUW8 2/20 0.40
▸ MAPK1 P28482 2/20 0.40
▸ MAPT P10636 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ RXFP1 Q9HBX9 1/20 0.40
▸ HPGD P15428 3/20 0.40
▸ ALDH1A1 P00352 2/20 0.40
▸ PIM1 P11309 3/20 0.39
▸ BIRC5 O15392 2/20 0.39
▸ LMNA P02545 1/20 0.39
▸ IL4 P05112 1/20 0.39
▸ SQOR Q9Y6N5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31695346 0.86 ATM (0.51) METKDRKDM4EGAAGLA
SCHEMBL31695345 0.84 ATM (0.50) METKDRKDM4EGAAGLA
SCHEMBL31695320 0.84 KDM4E (0.55) METKDRIKBKBKDM4EGAA
SCHEMBL31695348 0.82 PIM1 (0.47) METKDRADORA2AMAPTALDH1A1
SCHEMBL29335418 0.80 IL4 (0.54) KDM4EGAATDP1MAPTALDH1A1
SCHEMBL31695323 0.80 MAPT (0.50) METKDRKDM4EGAAGLA
SCHEMBL31695313 0.80 IL4 (0.54) KDM4EGAATDP1MAPTALDH1A1
SCHEMBL31695357 0.80 IL4 (0.45) KDM4EADORA2ATDP1MAPK1MAPT
SCHEMBL31695347 0.79 ALOX5 (0.49) METKDRMAPTNPSR1HPGD
SCHEMBL23841109 0.70 ATM (0.72) METKDRKDM4EGAAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313530-A1 SMALL MOLECULE INHIBITORS OF INTERLEUKIN-4 AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2025-10-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313530-A1 SMALL MOLECULE INHIBITORS OF INTERLEUKIN-4 AND USES THEREOF IL4, IRAK4, IL5 MET 1421/4885KDR 1239/4885IKBKB 93/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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