Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL4 | P05112 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 6/20 | 0.41 |
| ▸ | BIRC5 | O15392 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MET | P08581 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29335418 | 0.89 | IL4 (0.54) | IL4PIM1BIRC5ALDH1A1MAPT | |
| SCHEMBL31695313 | 0.89 | IL4 (0.54) | IL4PIM1BIRC5ALDH1A1MAPT | |
| SCHEMBL31695360 | 0.86 | IL4 (0.43) | IL4PIM1BIRC5ALDH1A1MAPT | |
| SCHEMBL31695335 | 0.83 | KDM4E (0.59) | IL4PIM1ALDH1A1MAPTKDM4E | |
| SCHEMBL31695352 | 0.83 | ACMSD (0.49) | IL4PIM1BIRC5ALDH1A1MAPT | |
| SCHEMBL23920029 | 0.81 | PIM1 (0.47) | PIM1BIRC5ALDH1A1MAPTKDM4E | |
| SCHEMBL31695295 | 0.81 | KDM4E (0.48) | IL4PIM1ALDH1A1MAPTKDM4E | |
| SCHEMBL23841138 | 0.80 | ATM (0.57) | PIM1BIRC5ALDH1A1MAPTKDM4E | |
| SCHEMBL31695348 | 0.79 | PIM1 (0.47) | IL4PIM1BIRC5ALDH1A1MAPT | |
| SCHEMBL31695294 | 0.78 | KDR (0.50) | PIM1ALDH1A1MAPTKDM4EMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250313530-A1 | SMALL MOLECULE INHIBITORS OF INTERLEUKIN-4 AND USES THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2025-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313530-A1 | SMALL MOLECULE INHIBITORS OF INTERLEUKIN-4 AND USES THEREOF | IL4, IRAK4, IL5 | IL4 1/4885PIM1 585/4885BIRC5 636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.