Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 5/20 | 0.69 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.68 |
| ▸ | HPGD | P15428 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | IL4 | P05112 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31695292 | 0.95 | ADORA1 (0.62) | ADORA1ADORA2AKDM4EHPGDALDH1A1 | |
| SCHEMBL31695344 | 0.94 | ADORA1 (0.61) | ADORA1ADORA2AKDM4EHPGDALDH1A1 | |
| SCHEMBL31695327 | 0.79 | KDM4E (0.66) | ADORA1ADORA2AKDM4EHPGDALDH1A1 | |
| SCHEMBL23833502 | 0.78 | IL4 (1.00) | ADORA1ADORA2AKDM4EHPGDALDH1A1 | |
| SCHEMBL23833503 | 0.78 | IL4 (1.00) | ADORA1ADORA2AKDM4EHPGDALDH1A1 | |
| SCHEMBL23841221 | 0.78 | IL4 (0.77) | ADORA1ADORA2AKDM4EHPGDALDH1A1 | |
| SCHEMBL31695325 | 0.75 | IL4 (0.72) | ADORA1ADORA2AKDM4EHPGDALDH1A1 | |
| SCHEMBL31695349 | 0.75 | IL4 (0.72) | ADORA1ADORA2AKDM4EHPGDALDH1A1 | |
| SCHEMBL31695332 | 0.74 | IL4 (0.78) | ADORA1ADORA2AKDM4EHPGDALDH1A1 | |
| SCHEMBL31695308 | 0.74 | ADORA1 (0.78) | ADORA1ADORA2AKDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250313530-A1 | SMALL MOLECULE INHIBITORS OF INTERLEUKIN-4 AND USES THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2025-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313530-A1 | SMALL MOLECULE INHIBITORS OF INTERLEUKIN-4 AND USES THEREOF | IL4, IRAK4, IL5 | ADORA1 3438/4885ADORA2A 3796/4885KDM4E 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.