Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 6/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | BIRC5 | O15392 | 2/20 | 0.56 |
| ▸ | MET | P08581 | 8/20 | 0.55 |
| ▸ | KDR | P35968 | 8/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23841105 | 0.88 | ATM (0.83) | PIM1ATMKMT2AKDM4EGAA | |
| SCHEMBL31695353 | 0.87 | ATM (0.61) | PIM1ATMKMT2AKDM4EGAA | |
| SCHEMBL23841104 | 0.87 | KMT2A (0.57) | PIM1ATMKMT2AKDM4EGAA | |
| SCHEMBL31695363 | 0.82 | MET (0.64) | PIM1ATMKMT2AKDM4EGAA | |
| SCHEMBL31695310 | 0.81 | KMT2A (0.63) | PIM1ATMKMT2AKDM4EGAA | |
| SCHEMBL23841103 | 0.81 | MET (0.67) | PIM1ATMKMT2AKDM4EGAA | |
| SCHEMBL23841110 | 0.77 | KDM4E (0.59) | PIM1ATMKMT2AKDM4EGAA | |
| SCHEMBL14944227 | 0.77 | KDM4E (0.78) | PIM1ATMKMT2AKDM4EGAA | |
| SCHEMBL25377987 | 0.75 | KDM4E (0.53) | PIM1ATMKMT2AKDM4EGAA | |
| SCHEMBL3838859 | 0.75 | ATM (0.67) | PIM1ATMKMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250313530-A1 | SMALL MOLECULE INHIBITORS OF INTERLEUKIN-4 AND USES THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2025-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313530-A1 | SMALL MOLECULE INHIBITORS OF INTERLEUKIN-4 AND USES THEREOF | IL4, IRAK4, IL5 | PIM1 585/4885ATM 1125/4885KMT2A 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.