Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 6/20 | 0.33 |
| ▸ | PRKCA | P17252 | 3/20 | 0.32 |
| ▸ | PRKCG | P05129 | 2/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | PRKCH | P24723 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.30 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGAV | P06756 | 1/20 | 0.30 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.30 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.30 |
| ▸ | ITGAL | P20701 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30706855 | 0.85 | CREBBP (0.32) | CREBBPIRAK4PRKCDPRKCAPRKCG | |
| SCHEMBL17137283 | 0.85 | PRKCD (0.37) | CREBBPIRAK4PRKCDPRKCAPRKCG | |
| SCHEMBL30706608 | 0.85 | CREBBP (0.32) | CREBBPIRAK4PRKCDPRKCAPRKCG | |
| SCHEMBL7507854 | 0.85 | PRKCD (0.37) | CREBBPIRAK4PRKCDPRKCAPRKCG | |
| SCHEMBL2793908 | 0.85 | PRKCD (0.37) | CREBBPIRAK4PRKCDPRKCAPRKCG | |
| SCHEMBL24250230 | 0.85 | CREBBP (0.32) | CREBBPPRKCDPRKCAPRKCGPRKD3 | |
| SCHEMBL8863388 | 0.82 | ITGB3 (0.46) | ITGB3ITGA2BITGB2ITGB1ITGAV | |
| SCHEMBL21338619 | 0.81 | IRAK4 (0.39) | IRAK4PRKCDPRKCAPRKCGPRKD3 | |
| SCHEMBL17137215 | 0.81 | IRAK4 (0.39) | IRAK4PRKCDPRKCAPRKCGPRKD3 | |
| SCHEMBL21338597 | 0.81 | IRAK4 (0.39) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025217141-A1 | PHARMACEUTICAL COMPOUNDS AND COMPOSITIONS AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 | ENANTA PHARMACEUTICALS, INC. (US) | 2025-10-16 | — | — | WO | disclosed |
| US-20250313569-A1 | Pharmaceutical Compounds And Compositions As Modulators Of MAS-Related G-Protein Receptor X2 | ENANTA PHARMACEUTICALS, INC. | 2025-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250313569-A1 | Pharmaceutical Compounds And Compositions As Modulators Of MAS-Related G-Protein Receptor X2 | MRGPRX2, MRGPRX1, MRGPRX4 | CREBBP 1164/4885IRAK4 1138/4885PRKCD 963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.