Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | EIF2AK4 | Q9P2K8 | 2/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 3/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31700958 | 0.95 | CYP11B2 (0.50) | CYP11B2EIF2AK4SCD5CYP3A4CYP2D6 | |
| SCHEMBL31702192 | 0.95 | CYP11B2 (0.54) | CYP11B2EIF2AK4SCD5CYP3A4CYP2D6 | |
| SCHEMBL31701150 | 0.95 | CYP11B2 (0.47) | CYP11B2EIF2AK4SCD5CYP3A4CYP2D6 | |
| SCHEMBL31701356 | 0.92 | CYP11B2 (0.48) | CYP11B2EIF2AK4SCD5CYP3A4CYP2D6 | |
| SCHEMBL31701479 | 0.83 | CYP11B2 (0.49) | CYP11B2SCD5CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL484892 | 0.78 | CYP11B2 (0.57) | CYP11B2EIF2AK4SCD5PARP1ACACB | |
| SCHEMBL31701313 | 0.77 | CYP2C19 (0.40) | CYP3A4CYP2D6CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL24746924 | 0.77 | CYP11B2 (0.49) | CYP11B2SCD5CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30064743 | 0.77 | CYP11B2 (0.49) | CYP11B2SCD5CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30328488 | 0.76 | CYP11B2 (0.48) | CYP11B2EIF2AK4SCD5CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250320204-A1 | 7-AZA BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS | RIBOSCIENCE LLC (US) | 2025-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250320204-A1 | 7-AZA BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS | ENPP1, ENPP3, PDE7A | CYP11B2 789/4885EIF2AK4 3961/4885SCD5 1796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.