Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30731986 | 0.84 | KDM4E (0.45) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL30731919 | 0.84 | KDM4E (0.45) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL31700753 | 0.82 | KDM4E (0.43) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL31702669 | 0.81 | KDM4E (0.42) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL31702535 | 0.81 | KDM4E (0.44) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL30794224 | 0.79 | NR1H2 (0.40) | KDM4EPKMHPGDRECQLMAPT | |
| SCHEMBL30731998 | 0.79 | NR1H2 (0.40) | KDM4EPKMHPGDRECQLMAPT | |
| SCHEMBL21980825 | 0.78 | GPR119 (0.42) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL412749 | 0.77 | HPGD (0.47) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL30020064 | 0.77 | KDM4E (0.40) | KDM4EPKMHPGDRECQLEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250320205-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250320205-A1 | STAT6 DEGRADERS | STAT6, STAT1, STAT5B | KDM4E 141/4885PKM 1276/4885HPGD 1586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.