Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31701125 | 0.91 | ALDH1A1 (0.65) | BRAFALDH1A1KDM4ENPSR1RXFP1 | |
| SCHEMBL31701624 | 0.90 | ALDH1A1 (0.64) | BRAFALDH1A1KDM4ENPSR1RXFP1 | |
| SCHEMBL31702266 | 0.85 | ALDH1A1 (0.64) | BRAFALDH1A1KDM4ENPSR1RXFP1 | |
| SCHEMBL31702048 | 0.84 | ALDH1A1 (0.56) | BRAFALDH1A1KDM4ENPSR1RXFP1 | |
| SCHEMBL29378520 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KDM4ENPSR1RXFP1TP53 | |
| SCHEMBL31700686 | 0.82 | ALDH1A1 (0.64) | BRAFALDH1A1KDM4ENPSR1RXFP1 | |
| SCHEMBL31700539 | 0.82 | ALDH1A1 (0.84) | BRAFALDH1A1KDM4ENPSR1RXFP1 | |
| SCHEMBL31701007 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KDM4ENPSR1RXFP1TP53 | |
| SCHEMBL31701605 | 0.78 | MAPT (0.66) | ALDH1A1KDM4ENPSR1RXFP1TP53 | |
| SCHEMBL8289336 | 0.78 | ALDH1A1 (0.76) | BRAFALDH1A1KDM4ENPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250319056-A1 | METHODS FOR TREATING CANCER | UNIV INDIANA TRUSTEES (US) | 2025-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250319056-A1 | METHODS FOR TREATING CANCER | HSP90AB1, HSP90B1, HSP90AB2P | BRAF 754/4885ALDH1A1 2316/4885KDM4E 3488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.