Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.84 |
| ▸ | HPGD | P15428 | 3/20 | 0.84 |
| ▸ | LMNA | P02545 | 2/20 | 0.84 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | BRAF | P15056 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31701605 | 0.87 | MAPT (0.66) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL31701020 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL31701604 | 0.82 | BRAF (0.67) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL29378520 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL31701125 | 0.80 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL31701624 | 0.79 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL31700686 | 0.78 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL31701007 | 0.77 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL8290769 | 0.77 | MAPT (0.79) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL8288650 | 0.77 | ALDH1A1 (0.68) | ALDH1A1KDM4EHPGDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250319056-A1 | METHODS FOR TREATING CANCER | UNIV INDIANA TRUSTEES (US) | 2025-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250319056-A1 | METHODS FOR TREATING CANCER | HSP90AB1, HSP90B1, HSP90AB2P | ALDH1A1 2316/4885KDM4E 3488/4885HPGD 1425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.