Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 8/20 | 0.36 |
| ▸ | KDM1B | Q8NB78 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25335478 | 0.93 | ROCK2 (0.42) | ROCK2KDM1AKDM1BKCNH2GAA | |
| SCHEMBL8244028 | 0.89 | HRH3 (0.36) | ROCK2KDM1AKDM1BKCNH2GAA | |
| SCHEMBL28974855 | 0.85 | ROCK2 (0.42) | ROCK2KDM1AKDM1BKCNH2GAA | |
| SCHEMBL29525834 | 0.85 | ROCK2 (0.46) | ROCK2KDM1AGAAMAPTKDM4E | |
| SCHEMBL10175794 | 0.85 | ROCK2 (0.46) | ROCK2KDM1AGAAMAPTKDM4E | |
| SCHEMBL22724888 | 0.85 | KDM1A (0.33) | KDM1AKDM1BKCNH2PIM1 | |
| SCHEMBL23175499 | 0.79 | CA1 (0.37) | GAAMAPTKDM4EALOX15CA12 | |
| SCHEMBL20337719 | 0.79 | ROCK2 (0.39) | ROCK2KDM1AKDM1BKCNH2GAA | |
| SCHEMBL31149474 | 0.79 | ROCK2 (0.39) | ROCK2KDM1AKDM1BKCNH2GAA | |
| SCHEMBL20349186 | 0.78 | GAA (0.46) | ROCK2GAAMAPTKDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260014147-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2026-01-15 | — | — | US | disclosed |
| US-20250325677-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-23 | — | — | US | disclosed |
| US-20250320206-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250325677-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | ROCK2 4018/4885KDM1A 174/4885KDM1B 133/4885 |
| US-20260014147-A1 | STAT6 DEGRADERS | STAT6, NCOR1, CBR1 | ROCK2 3972/4885KDM1A 569/4885KDM1B 673/4885 |
| US-20250320206-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | ROCK2 4018/4885KDM1A 174/4885KDM1B 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.