SCHEMBL3170254

SCHEMBL3170254

Cc1cc2c(cc1Br)C(C)(C)CCC2(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 19/20 0.44
RXRG P48443 9/20 0.42
RXRB P28702 8/20 0.42
RARA P10276 5/20 0.42
RARB P10826 4/20 0.42
RARG P13631 4/20 0.42
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
MEN1 O00255 1/20 0.40
CYP26A1 O43174 1/20 0.40
ABCB11 O95342 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21238596 0.86 BCHE (0.37) RXRARXRGRXRBRARARARB
SCHEMBL6678059 0.85 RXRA (0.49) RXRARXRGRXRBRARARARB
SCHEMBL6449453 0.83 RXRA (0.38) RXRARXRGRXRBRARARARB
SCHEMBL7622765 0.83 RXRA (0.48) RXRARXRGRXRBRARARARB
SCHEMBL8200212 0.80 RXRA (0.42) RXRARXRGRXRBRARARARB
SCHEMBL6449415 0.79 RXRA (0.41) RXRARXRGRXRBRARARARB
SCHEMBL25129965 0.79 RXRA (0.45) RXRARXRGRXRBRARARARB
SCHEMBL29608697 0.79 RXRA (0.45) RXRARXRGRXRBRARARARB
SCHEMBL29539383 0.77 CYP3A4 (0.44) RXRARXRGRXRBRARARARB
SCHEMBL330594 0.77 CYP3A4 (0.44) RXRARXRGRXRBRARARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118871419-A Novel compound and organic light emitting device comprising the same 株式会社LG化学 2024-10-29 CN disclosed
CN-118715199-A Novel compound and organic light emitting device comprising the same 株式会社LG化学 2024-09-27 CN disclosed
CN-117616006-A Compound and organic light emitting device comprising the same 株式会社LG化学 2024-02-27 CN disclosed
CN-117561234-A Compound and organic light emitting device comprising the same 株式会社LG化学 2024-02-13 CN disclosed
WO-2023239091-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2023-12-14 WO disclosed
WO-2023239092-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2023-12-14 WO disclosed
WO-2023239092-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2023-12-14 WO disclosed
WO-2023239091-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2023-12-14 WO disclosed
EP-4265624-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME Lg Chem, Ltd. (KR) 2023-10-25 EP disclosed
WO-2023200225-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-10-19 WO disclosed
EP-0661258-A1 Biaromatic propynyl compounds, pharmaceutical compositions and cosmetics containing them and their uses CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) 1995-07-05 EP disclosed
WO-1995004036-A1 COMPOUNDS HAVING SELECTIVE ACTIVITY FOR RETINOID X RECEPTORS, AND MEANS FOR MODULATION OF PROCESSES MEDIATED BY RETINOID X RECEPTORS LIGAND PHARMACEUTICALS INC. (US) 1995-02-09 WO disclosed
EP-0637297-A1 COMPOUNDS HAVING SELECTIVITY FOR RETINOID X RECEPTORS LIGAND PHARMACEUTICALS, INC. (US) 1995-02-08 EP disclosed
WO-1994015902-A1 COMPOUNDS HAVING SELECTIVITY FOR RETINOID X RECEPTORS LIGAND PHARMACEUTICALS INC. (US) 1994-07-21 WO disclosed
WO-1994015901-A1 COMPOUNDS HAVING SELECTIVITY FOR RETINOID X RECEPTORS LIGAND PHARMACEUTICALS INC. (US) 1994-07-21 WO disclosed
WO-1993021146-A1 COMPOUNDS HAVING SELECTIVITY FOR RETINOID X RECEPTORS LIGAND PHARMACEUTICALS INCORPORATED (US) 1993-10-28 WO disclosed
EP-0137010-A4 NAPHTHYL OR TETRAHYDRONAPHTHYL-SUBSTITUTED NAPHTHOIC ACID AND DE RIVATES. STANFORD RES INST INT (US) 1985-08-12 EP disclosed
EP-0137010-A1 NAPHTHYL OR TETRAHYDRONAPHTHYL-SUBSTITUTED NAPHTHOIC ACID AND DE RIVATES SRI INTERNATIONAL (US) 1985-04-17 EP disclosed
WO-1984003505-A1 NAPHTHYL OR TETRAHYDRONAPHTHYL-SUBSTITUTED NAPHTHOIC ACID AND DE RIVATES STANFORD RES INST INT (US) 1984-09-13 WO disclosed
US-4454341-A ANTITUMOR, SKIN DISORDERS SRI INTERNATIONAL (US) 1984-06-12 US disclosed