SCHEMBL330594

SCHEMBL330594

Cc1cc2c(cc1N)C(C)(C)CCC2(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.44
TSHR P16473 2/20 0.44
MAPK1 P28482 1/20 0.44
RXRA P19793 16/20 0.42
RXRG P48443 9/20 0.42
RXRB P28702 8/20 0.42
RARA P10276 4/20 0.42
RARB P10826 3/20 0.42
RARG P13631 3/20 0.42
ALDH1A1 P00352 2/20 0.41
CYP1A2 P05177 1/20 0.41
ALOX15 P16050 1/20 0.41
CASP7 P55210 1/20 0.41
HIF1A Q16665 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 1/20 0.40
CYP26A1 O43174 1/20 0.40
ABCB11 O95342 1/20 0.40
ESR1 P03372 1/20 0.40
PGR P06401 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29539383 1.00 CYP3A4 (0.44) CYP3A4TSHRMAPK1RXRARXRG
SCHEMBL9867812 0.85 PTK2 (0.44) CYP3A4RXRARXRGRXRBRARA
SCHEMBL7622765 0.83 RXRA (0.48) RXRARXRGRXRBRARARARB
SCHEMBL31675854 0.80 RXRA (0.42) CYP3A4RXRARXRGRXRBRARA
SCHEMBL9054373 0.80 RXRA (0.42) CYP3A4RXRARXRGRXRBRARA
SCHEMBL3170254 0.77 RXRA (0.44) RXRARXRGRXRBRARARARB
SCHEMBL21440625 0.77 RXRA (0.38) CYP3A4RXRARXRGRXRBRARA
SCHEMBL6330023 0.77 RXRA (0.48) CYP3A4TSHRMAPK1RXRARXRG
SCHEMBL9867919 0.76 RXRA (0.44) CYP3A4RXRARXRGRXRBRARA
SCHEMBL9053254 0.76 GAA (0.46) CYP3A4TSHRMAPK1RXRARXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637482-B2 Compound and organic light emitting device comprising same LG CHEM, LTD. (KR) 2026-05-26 US disclosed
US-12559467-B2 Organic light emitting device LG CHEM, LTD. (KR) 2026-02-24 US disclosed
US-12563964-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2026-02-24 US disclosed
US-12522764-B2 Compound and organic light emitting device comprising same LG CHEM, LTD. (KR) 2026-01-13 US disclosed
US-12497415-B2 Polycyclic compound and organic light-emitting element comprising same LG CHEM, LTD. (KR) 2025-12-16 US disclosed
EP-3919500-B1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2024-08-28 EP disclosed
EP-3909958-B1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2023-12-27 EP disclosed
EP-4265624-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME Lg Chem, Ltd. (KR) 2023-10-25 EP disclosed
US-11780856-B2 Compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2023-10-10 US disclosed
US-11780856-B2 Compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2023-10-10 US disclosed
EP-1510210-A1 IMMUNITY-RELATED PROTEIN KINASE INHIBITORS Institute of Medicinal Molecular Design, Inc. (JP) 2005-03-02 EP disclosed
US-20040259877-A1 Inhibitors against the production and release of inflammatory cytokines INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2004-12-23 US disclosed
EP-1352650-A1 INHIBITORS AGAINST THE PRODUCTION AND RELEASE OF INFLAMMATORY CYTOKINES Institute of Medicinal Molecular Design, Inc. (JP) 2003-10-15 EP disclosed
EP-1180520-A1 HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES Institute of Medicinal Molecular Design, Inc. (JP) 2002-02-20 EP disclosed
US-5498755-A IMINE COMPOUNDS FOR SKIN DISORDERS AND ANTIINFLAMMATORY AGENTS ALLERGAN, INC. 1996-03-12 US disclosed
WO-1996006070-A1 DISUBSTITUTED ARYL AND HETEROARYL IMINES HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY ALLERGAN (US) 1996-02-29 WO disclosed
US-RE33533-E Skin disorders CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) 1991-02-05 US disclosed
EP-0292348-B1 POLYCYCLIC HETEROCYCLIC DERIVATIVES, PROCES FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINES CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA Groupement d'Intérêt Economique dit: (FR) 1990-09-19 EP disclosed
US-4874747-A DERMATOLOGY CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) 1989-10-17 US disclosed
EP-0292348-A1 Polycyclic heterocyclic derivatives, proces for their preparation and their use in human and veterinary medicines CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA Groupement d'Intérêt Economique dit: (FR) 1988-11-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637482-B2 Compound and organic light emitting device comprising same NR1H2, NR1H3, NR2E3 CYP3A4 638/4885TSHR 175/4885MAPK1 4353/4885
US-12497415-B2 Polycyclic compound and organic light-emitting element comprising same CYBA, CRY2, CRY1 CYP3A4 7/4885TSHR 4014/4885MAPK1 2779/4885
US-12563964-B2 Organic light-emitting device CRY1, CYP1A1, CTNNA1 CYP3A4 126/4885TSHR 2629/4885MAPK1 874/4885
US-11780856-B2 Compound and organic light-emitting device comprising same CRY1, CRY2, LEF1 CYP3A4 27/4885TSHR 4847/4885MAPK1 277/4885
US-12559467-B2 Organic light emitting device CRY1, RPS24, ARL1 CYP3A4 678/4885TSHR 1707/4885MAPK1 2213/4885
US-20040259877-A1 Inhibitors against the production and release of inflammatory cytokines NFKBIA, IL1B, IKBKB CYP3A4 1988/4885TSHR 4035/4885MAPK1 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.