Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.44 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.42 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.42 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.42 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250720 | 0.82 | NCF1 (0.44) | HRH3DYRK3CDK1CDK2GSK3B | |
| SCHEMBL31703336 | 0.82 | NCF1 (0.44) | HRH3DYRK3CDK1CDK2GSK3B | |
| SCHEMBL155961 | 0.79 | HRH3 (0.65) | HRH3DYRK3CDK1CDK2GSK3B | |
| SCHEMBL1570308 | 0.77 | HRH3 (0.45) | HRH3DYRK3CDK1CDK2GSK3B | |
| SCHEMBL29809064 | 0.77 | NCF1 (0.60) | HRH3CDK1CDK7SMN1; SMN2NPC1 | |
| SCHEMBL13834647 | 0.77 | NCF1 (0.60) | HRH3CDK1CDK7SMN1; SMN2NPC1 | |
| SCHEMBL23239918 | 0.76 | HRH3 (0.51) | HRH3L3MBTL1TMEM97SIGMAR1CYP2A13 | |
| SCHEMBL23213253 | 0.76 | HRH3 (0.51) | HRH3L3MBTL1TMEM97SIGMAR1CYP2A13 | |
| SCHEMBL29796217 | 0.76 | HRH3 (0.51) | HRH3L3MBTL1TMEM97SIGMAR1CYP2A13 | |
| SCHEMBL249180 | 0.76 | ALDH1A1 (0.57) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215121-A1 | HEDGEHOG ACYLTRANSFERASE INHIBITORS | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2025-10-16 | — | — | WO | disclosed |