Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.67 |
| ▸ | BACE1 | P56817 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31703309 | 0.87 | ALDH1A1 (0.74) | MEN1KMT2AKDM4EALDH1A1ADRB2 | |
| SCHEMBL31703255 | 0.85 | KDM4E (0.72) | ACHEBACE1MEN1KMT2AKDM4E | |
| SCHEMBL31703155 | 0.81 | MAPT (0.77) | MEN1KMT2AKDM4EALDH1A1ADRB2 | |
| SCHEMBL31703482 | 0.81 | KDM4E (0.67) | ACHEBACE1MEN1KMT2AKDM4E | |
| SCHEMBL23495308 | 0.75 | ALDH1A1 (0.81) | MEN1KMT2AKDM4EALDH1A1ADRB2 | |
| SCHEMBL29436176 | 0.75 | ALDH1A1 (0.81) | MEN1KMT2AKDM4EALDH1A1ADRB2 | |
| SCHEMBL5579936 | 0.75 | HTT (0.69) | MEN1KMT2AKDM4EALDH1A1ADRB2 | |
| SCHEMBL29436214 | 0.74 | KDM4E (0.58) | MEN1KMT2AKDM4EALDH1A1ADRB2 | |
| SCHEMBL23495306 | 0.74 | KDM4E (0.58) | MEN1KMT2AKDM4EALDH1A1ADRB2 | |
| SCHEMBL23495113 | 0.74 | KDM4E (0.60) | MEN1KMT2AKDM4EALDH1A1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215121-A1 | HEDGEHOG ACYLTRANSFERASE INHIBITORS | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2025-10-16 | — | — | WO | disclosed |