Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.74 |
| ▸ | PKM | P14618 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31703255 | 0.92 | KDM4E (0.72) | ALDH1A1KDM4EMEN1KMT2AADRB2 | |
| SCHEMBL31703482 | 0.88 | KDM4E (0.67) | ALDH1A1KDM4EMEN1KMT2AADRB2 | |
| SCHEMBL31703155 | 0.88 | MAPT (0.77) | ALDH1A1KDM4EMEN1KMT2AADRB2 | |
| SCHEMBL31703498 | 0.87 | ACHE (0.67) | ALDH1A1KDM4EMEN1KMT2AADRB2 | |
| SCHEMBL31703451 | 0.85 | ACHE (0.68) | ALDH1A1KDM4EMEN1KMT2AADRB2 | |
| SCHEMBL31703313 | 0.85 | KDM4E (0.66) | ALDH1A1KDM4EMEN1KMT2AADRB2 | |
| SCHEMBL31703490 | 0.85 | KDM4E (0.66) | ALDH1A1KDM4EMEN1KMT2AADRB2 | |
| SCHEMBL23202557 | 0.84 | KDM4E (0.69) | ALDH1A1KDM4EMEN1KMT2AADRB2 | |
| SCHEMBL31096525 | 0.84 | KDM4E (0.69) | ALDH1A1KDM4EMEN1KMT2AADRB2 | |
| SCHEMBL5579936 | 0.84 | HTT (0.69) | ALDH1A1KDM4EMEN1KMT2AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215121-A1 | HEDGEHOG ACYLTRANSFERASE INHIBITORS | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2025-10-16 | — | — | WO | disclosed |